ince intravascular ultrasound (IVUS) was introduced in the early 1990 s,1,2 it has been used not only as an adjunctive device to percutaneous coronary interventions (PCI), but also as a research tool to evaluate vessel structure in detail. Although IVUS has helped broaden our understanding of coronary artery structure, its limited spatial resolution does not allow for the assessment of microstr...

Optical Doppler tomography (ODT) is an imaging modality that takes advantage of the short coherence length of a broad-band light sources to perform micrometer-scale, crosssectional imaging of tissue structure and blood flow dynamics simultaneously. We review in this paper the principal of ODT and its applications. Results from in vitro and in vivo model studies demonstrated that ODT can map the...

An experimental tracking optical coherence tomography (OCT) system has been clinically tested. The prototype instrument uses a secondary sensing beam and steering mirrors to compensate for eye motion with a closed-loop bandwidth of 1 kHz and tracking accuracy, to within less than the OCT beam diameter. The retinal tracker improved image registration accuracy to <1 transverse pixel (<60 microm)....

Optical coherence tomography (OCT) is an optical signal acquisition and processing method. It captures micrometer-resolution, three-dimensional images from within optical scattering media (e.g., biological tissue). Optical coherence tomography is an interferometric technique, typically employing near-infrared light. The use of relatively long wavelength light allows it to penetrate into the sca...

Abstract Integrating all optical components of an coherence tomography (OCT) device into a single chip is non-trivial and challenging job. The design development such lab-on-a possible only via Micro-Opto-Electro-Mechanical System (MOEMS) technology. reproducible integrated fabrication would reduce cost size many folds as compared to bulk or fiber optic OCT system. A miniaturized less than 5mm ...

Functional optical coherence tomography (fOCT) is used to record optical changes that correspond to spontaneous and stimulated electrical activity in neural tissue. FOCT provides a high-resolution, real-time, non-invasive method for investigating neurophysiology. 2003 Optical Society of America OCIS codes: (170.4500) Optical coherence tomography; (170.3880) Medical and biological imaging; (170...

This paper gives an introduction to optical coherence tomography (OCT), explains its basic principles, and discusses the information content of OCT images. Various interferometric techniques used in OCT are reviewed and a short survey of results obtained so far in different fields of application and possible future developments are presented.

Optical Coherence Tomography (OCT) has revolutionized ophthalmology. Since its introduction in the early 1990s it has continuously improved in terms of speed, resolution and sensitivity. The technique has also seen a variety of extensions aiming to assess functional aspects of the tissue in addition to morphology. One of these approaches is Doppler OCT (DOCT), which aims to visualize and quanti...

The coherence of an optical beam having multiple degrees of freedom (DoFs) is described by a coherency matrix G spanning these DoFs. This optical coherency matrix has not been measured in its entirety to date--even in the simplest case of two binary DoFs where G is a 4 × 4 matrix. We establish a methodical yet versatile approach--optical coherency matrix tomography--for reconstructing G that ex...