BACKGROUND Ocular involvement in pregnancy-induced hypertension (PIH) is common. OBJECTIVE To study the association between pregnancy-induced hypertensive fundus changes and fetal outcomes. SUBJECTS AND METHODS A prospective cohort study was carried out including 153 subjects with the diagnosis of PIH. The subjects were evaluated for hypertensive fundus changes. Fetal outcomes were assessed...

the purpose of this study was to investigate magnetic resonance imaging (mri) of the normal feline eyeand optic nerves using t1-weighted and t2-weighted images. a total of 6 healthy female domestic short haircats age 2-2.5 years and weighing 3.2 ± 0.4 kg were selected. magnetic resonance imaging data werecollected using gemsow (philips) at a magnetic field strength of 1.5 t. dorsal, sagittal, a...

Glaucoma is the second leading cause of loss of vision in the world. Examining the head of optic nerve (cup-to-disc ratio) is very important for diagnosing glaucoma and for patient monitoring after diagnosis. Images of optic disc and optic cup are acquired by fundus camera as well as Optical Coherence Tomography. The optic disc and optic cup segmentation techniques are used to isolate the relev...

1. Lincoff H, Lopez R, Kreissig I, Yannuzzi L, Cox M, Burton T. Retinoschisis associated with optic nerve pits. Arch Ophthalmol. 1988;106:6167. 2. Spaide RF, Costa DL, Huang SJ. Macular schisis in a patient without an optic disk pit optical coherence tomographic findings. Retina. 2003; 23:238-240. 3. Rutledge BK, Puliafito CA, Duker JS, Hee MR, Cox MS. Optical coherence tomography of macular le...

background :there is not any data available about the effect of high bar pressure condition on intracranial pressure. in this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated.   methods : twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. only one person ...

PURPOSE To determine whether inducible nitric oxide synthase (NOS-2) is involved in glaucomatous optic neuropathy. METHODS Chronic elevation of rat intraocular pressure (IOP) leading to optic nerve damage was induced by episcleral injection of hypertonic saline, which caused sclerosis and blockade of aqueous humor outflow pathways. Expression of NOS-2 in the retina and optic nerve head (ONH) ...

1) Evaluation of the Optic Nerve requires descriptive quantitative and qualitative intrapapillary and parapapillary regions of the optic nerve head and the retinal nerve fiber layer (RNFL)variables including: a. Size and shape of the optic disc b. Size, shape and pallor of the neuroretinal rim c. Configuration and depth of the optic cup d. Cup-disc diameter ratio and cup-disc area ratio e. Posi...

Primary open-angle glaucoma is a progressive optic neuropathy involving loss of retinal ganglion cells and their axons at the level of the optic nerve head. This change manifests as thinning and excavation of the neural tissues and nerve fiber layer. Therefore, it has long been known that the structural appearance of the optic nerve head is paramount to both glaucoma diagnosis and to the detect...

PURPOSE Remodeling of the extracellular matrix occurs in the lamina cribrosa in progressed glaucomatous optic nerve damage including disc cupping. We examined immunohistochemical changes in the transforming growth factor (TGF)-beta and platelet-derived growth factor (PDGF) in the optic nerve head in an experimentally induced glaucoma model. METHODS We used 3 cynomolgus and 2 Japanese monkey e...

Purpose Large trans-lamina cribrosa pressure differences (TLCPD) have been suggested to play a role in the development of normal-tension glaucoma. To avoid substantial increases TLCPD upright postures, we hypothesize that collapse optic nerve subarachnoid space (ONSAS) protects eyes from large TLCPDs when stand up, i.e., by preventing low cerebrospinal fluid pressures around nerve. In this stud...