AIMS/BACKGROUND Visual symptoms are a common but not invariable feature of Alzheimer's disease (AD) and such symptoms appear to become more pronounced as the severity of the dementia increases. Pathology in both the pregeniculate and cortical parts of the visual system has been suggested to underlie the visual deficits in AD. In order to investigate the former possibility, the effect of AD on t...

Acousto-optical coherence tomography (AOCT) is a variant of acousto-optic imaging (also called ultrasonic modulation imaging) that makes it possible to get the z resolution with acoustic and optic continuous wave beams. We describe here theoretically the AOCT effect, and we show that the acousto-optic "tagged photons" remain coherent if they are generated within a specific z region of the sampl...

We report the observation of a biaxial nematic phase in a bent-core molecular system using polarizing microscopy, electro-optics, and dielectric spectroscopy, where we find that the biaxiality exists on a microscopic scale. An application of electric field induces a macroscopic biaxiality and in consequence gives rise to electro-optic switching. This electro-optic effect shows significant poten...

treated with corticosteroids was found to have a statistically significant higher mortality rate compared to the placebo group [4]. This means that not only is the treatment with high dose corticosteroids not beneficial in cases of TON, it may in fact be harmful when given to patients with severe head trauma and brain injury. We present the case of a patient with bilateral TON. Bilateral TON is...

PURPOSE To evaluate the effects of signal strength, age, sex, optic disc size, and axial length on the normal optic nerve head (ONH), retinal nerve fiber layer (RNFL), and macular measurements with spectral domain optical coherence tomography (SD-OCT). METHODS In an observational, cross-sectional study, 119 eyes of 60 normal subjects of Indian origin underwent ONH, RNFL, and macular imaging w...

A fundamental issue in central nervous system development regards the effect of target tissue on the differentiation of innervating neurons. We address this issue by characterizing the role the retinal ganglion cell target, i.e., the optic tectum, plays in regulating expression of tubulin and nicotinic acetylcholine receptor genes in regenerating retinal ganglion cells. Tubulins are involved in...

We demonstrate a novel platform to control the thermo-optic sensitivity in nanophotonic devices by evanescent coupling of light with bimaterial cantilevers. The cantilever can be designed to provide a negative thermal feedback to passively compensate for the positive thermo-optic effect in the waveguide core. We demonstrate athermal operation over 14 deg in cantilever coupled Silicon ring reson...

Ethambutol and isoniazid are antimicrobial agents used to treat multi-drug-resistant tuberculosis. The most commonly recognized toxic effect of these drugs is optic neuropathy, usually manifesting as a decrease in visual acuity, deficits in color vision and ceco central scotomas. Total visual loss is a rare complication that can be related to ethambutol and isoniazid toxicity. As precipitating ...

Nonlinear Magneto-Optic Effects with Ultra-Narrow Widths Dmitry Budker , Valeriy Yashchuk , and Max Zolotorev a Department of Physics, University of California, Berkeley, California 94720-7300 b E. O. Lawrence Berkeley National Laboratory, Berkeley, California 94720 c B. P. Konstantinov Petersburg Nuclear Physics Institute, Gatchina, Russia 188350 Abstract Several dispersion-like features in th...