PURPOSE To describe optic disc variables assessed by evaluation of clinical optic disc photographs and to compare sensitivity and specificity of these optic disc parameters in identifying patients with ocular hypertension who have nerve fiber layer defects and normal visual fields and patients with visual field defects. METHODS The study included 500 normal subjects, 132 patients with ocular ...

Glaucoma can be diagnosed as a group of conditions that share a characteristic topographic change at the optic nerve head (glaucomatous cupping) and pattern of visual loss (glaucomatous visual field defect). Usually the intraocular pressure (IOP) lies above the normal range. For a common complaint, the existence of which has been known for centuries, we ophthalmologists are not good at identify...

To our knowledge, this case report describes the first instance of reversal glaucomatous optic nerve cupping in a young adult with rare form juvenile open-angle glaucoma (JOAG) associated novel variant myocilin gene (MYOC). This 25-year-old woman severe-stage MYOC-associated JOAG presented blurry vision and intermittent pain her left eye. She had strong family history multiple first-degr...

AIMS/BACKGROUND It has been reported that the number of optic nerve fibres decrease with age, and the cup/disc (C/D) ratio increases as the optic disc size increases. Consequently, the normal value of the optic disc variables measured by an optic disc analyser may change according to the optic disc size or age. The effect of individual variations in optic disc size or age on interpretation of o...

Optic disc pit and optic nerve coloboma are examples of congenital optic disc abnormalities. Although optic nerve coloboma can be inherited in an autosomal dominant fashion, no conclusive link has been found in the case of optic disc pit as an autosomal dominant disease. We describe two cases: a daughter with an optic disc pit complicated by maculopathy and her mother with a congenitally abnorm...

The objective is to report a 33 year old female who came to the emergency room of Ophthalmology complaining of reduced visual acuity on the left eye, in a progressive and insidious way, about two years ago. In the ophthalmological examination, she presented dilated tortuous vessels in her left bulbar conjunctiva, very high intraocular pressure and increased cupping of the optic disc. SITASWAP a...

The development of fluorescein angiography has stimulated a great deal of interest in the vascular physiology of the retina and choroid by providing a method for examining different aspects of the ocular circulation in vivo. Of particular interest is the role of the blood supply to the optic disc in the production of field defects in glaucoma, and its relationship to pathological disc cupping (...

Goniodysgenesis, malformation of the filtration angle, was observed in a New Zealand white rabbit supplied with 100 g/day rabbit chow containing 0.2% cholesterol for 10 months. Histopathology revealed cupping of the optic disc, atrophy of the retina and hyalinization of the ciliary body in the bilateral eyeballs. These findings corresponded with histopathological features caused by glaucoma. On...

This article reports a case of possible involvement of membrane tissue on the optic disc with macular schisis formation associated with glaucomatous optic disc without optic disc pits. A 78-year-old man presented with loss of central visual acuity of the left eye. He had a medical history of primary open-angle glaucoma. Visual acuity was 0.6 in his left eye, and funduscopy revealed macular schi...