Three patients with acute oropharyngeal palsy had high titre anti-GQ1b and anti-GT1a IgG antibodies. No patients had ophthalmoplegia or ptosis. In all patients limb ataxia or areflexia were present without notable limb weakness. These patients describe an oropharyngeal variant of Guillain-Barré syndrome in terms of anti-GQ1b antibody reactivity and show that high titre anti-GQ1b antibodies, ser...

CASE REPORT A 20 year-old woman was submitted to resection of an ependymome of the fourth ventricle. After surgery the patient began to refer diplopia and oscillopsia. WEBINO syndrome (wall-eyed bilateral internuclear ophthalmoplegia), vertical nystagmus and skew deviation were diagnosed. DISCUSSION WEBINO syndrome is considered a special form of bilateral internuclear ophthalmoplegia. It is ...

The Kearns-Sayre syndrome is a neuromyopathic disorder associated with mitochondrial abnormalities and characterized by the triad of chronic external ophthalmoplegia, atypical pigmentary retinopathy, and progressive conduction system disorders. Ragged red muscle fibers that seem to contain an excess of altered mitochondria are observed. The disease affects both sexes alike, during the first or ...

Acquired isolated ophthalmoplegia in childhood has many potential causes. Although other ophthalmological or clinical features may aid lesion localisation, the absence of these does not preclude structural pathology. Two cases of cavernous sinus pseudotumour presented as ophthalmoplegia with and without pain. Magnetic resonance imaging of the cavernous sinus revealed the presence of enhancing t...

Dear Editor: Tolosa-Hunt syndrome (THS) and diabetes mellitus (DM) are relatively common etiologies of painful ophthalmoplegia (PO). However, distinguishing diabetic ophthalmoplegia from THS or recurrent painful ophthalmoplegic neuropathy (RPON) is sometimes difficult because they demonstrate similar clinical courses and DM existence does not necessarily confirm the diagnosis of diabetic ophtha...

A 14 year old boy with atypical myasthenia gravis is reported. The interesting features of the case were the onset in first decade with progressive weakness of limb muscles simulating limb girdle myopathy, presence of bilateral symmetrical non fluctuating external ophthalmoplegia with ptosis and the absence of diplopia. Differential response to choline esterase inhibitors was clinically apparen...

Ocular signs are common in systemic sarcoidosis. Upwards of 50 per cent. of affected patients develop a granulomatous anterior uveitis, and fundus lesions are frequently observed. Ocular findings due to central nervous system involvement are less frequent, but can be the initial complaint. The subject of central nervous system involvement in sarcoidosis has been reviewed by Colover (I948) and W...

A 21-year-old woman presented to the emergency department 1 day after a fall. On the day of presentation, she awoke with horizontal diplopia and posterior neck pain. Based on clinical findings, she was diagnosed with bilateral internuclear ophthalmoplegia. A conventional angiogram identified a left vertebral artery dissection. She was started on anticoagulant therapy, with gradual improvement o...