نتایج جستجو برای: oocyte secreted factor
تعداد نتایج: 886795 فیلتر نتایج به سال:
Multiple ribonucleases are widely found in living organisms, but the function and regulation of individual ribonucleases are still not clear. In the present study, we found that one oocytic ribonuclease, RC-RNase, is developmentally expressed in the liver and stored in the oocyte of the bullfrog, while another ribonuclease, RC-RNase L1, is constitutively expressed and retained in the liver at a...
During meiotic maturation, the cortical cytokeratin filament system of the Xenopus oocyte disappears (Klymkowsky, M. W., and L. A. Maynell. 1989. Dev. Biol. 134:479). Here we demonstrate that this disappearance results from the severing of cytokeratin filaments into a heterogenous population of oligomers, with S- values ranging from 12S and greater. Cytokeratin filament severing correlates with...
OBJECTIVE To compare the oocyte-activating ability of whole human round spermatids and their isolated nuclei. DESIGN Prospective study using sibling oocytes from patients undergoing spermatid conception and intracytoplasmic sperm injection treatment cycles. SETTING Private assisted reproduction laboratories and a university department. PATIENT(S) Couples with male infertility. INTERVENT...
JMY is a transcriptional co-factor of p53. Latest work has revealed that JMY is also an actin nucleation factor that regulates new filament assembly and activates Arp2/3 complex in somatic cells; however, roles of JMY in mouse oocyte are unknown. Here we showed the expression and functions of JMY during mouse oocyte meiotic maturation. JMY mRNA is expressed largely from germinal vesicle to meta...
The establishment of the anterior-posterior (AP) axis in Drosophila melanogaster requires signaling between the oocyte and surrounding somatic follicle cells during oogenesis [1] [2]. First, a signal from the oocyte (Gurken (Grk), a transforming growth factor-alpha (TGFalpha) homolog) is received by predetermined terminal follicle cells in which the epidermal growth factor receptor (EGFR) pathw...
OBJECTIVE To determine the effect of infertility-linked sperm phospholipase Cζ (PLCζ) mutations on their ability to trigger oocyte Ca(2+) oscillations and development, and also to evaluate the potential therapeutic utility of wild-type, recombinant PLCζ protein for rescuing failed oocyte activation and embryo development. DESIGN Test of a novel therapeutic approach to male factor infertility....
Background: Oocyte donation and assisted reproductive technology (ART) give women with ovarian failure, advanced reproductive age, inheritable disorders or recurrent implantation failure, the ability to conceive. The success of oocyte donation is reportedly influenced by multiple parameters of the oocyte donor and recipient. The objective of this study was to evaluate the donor and recipient va...
Introduction & Objective: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. According to the Rotterdam criteria, this syndrome is identified by presence of two of three criteria: (1) polycystic ovaries (2) oligo/anovulation and/or (3) clinical or biochemical evidence of hyperandrogenism. Low mature oocyte and embryo have been reported in poly...
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