How does the nervous system encode complex sensory stimuli? A recent study reveals the fly olfactory system compensates for variability in sensory input as odor representations are restructured for enhanced discriminability and coding efficiency.

In Drosophila melanogaster, gender-specific behavioural responses to the male-produced sex pheromone cis-vaccenyl acetate (cVA) rely on sexually dimorphic, third-order neural circuits. We show that nutritional state in female flies modulates cVA perception in first-order olfactory neurons. Starvation increases, and feeding reduces attraction to food odour, in both sexes. Adding cVA to food odou...

The olfactory system becomes more sensitive when odor inputs are weak, and less sensitive when confronted with strong odors.

The clinical effects of the Covid-19 pandemic are now subject numerous studies worldwide. But what quarantine imposed by states that implemented measures lockdown? present research aims to explore, in a preliminary way, major stress-related symptoms during lockdown, due Covid-19, Italian population. Subjects were asked fill out survey, traced line identifying most relevant psychophysiological t...

Emotions have a strong influence on the perception of visual and auditory stimuli. Only little is known about the relation between emotional stimulation and olfactory functions. The present study investigated the relationship between the presentation of affective pictures, olfactory functions, and sex. Olfactory performance was assessed in 32 subjects (16 male). Olfactory sensitivity was signif...

Insulin is an important peptide hormone that regulates food intake and olfactory function. While a multitude of studies investigated the effect of insulin in the olfactory bulb and olfactory epithelium, research on how it modulates higher olfactory centers is lacking. Here we investigate how insulin modulates neural activity of pyramidal neurons in the anterior piriform cortex, a key olfactory ...

Olfactory perception is mediated by a multitude of olfactory receptors, whose expression in the sensory surface, the olfactory epithelium, is spatially regulated. A common theme is the segregation of different olfactory receptors in different expression domains, which in turn leads to corresponding segregation in the neuronal responses to different odor groups. The amphibian olfactory receptor ...

Whether a system of imagery for olfaction exists is currently an unsettled issue. Moreover, the dimensions underlying odor perception have eluded researchers for many years. Two experiments bearing on these issues are presented. In one experiment, a group of 32 undergraduates rated the similarity of pairs of 16 commonplace odorants (e.g., chocolate and leather) they perceived using scratch and ...

Our olfactory system is confronted with complex mixtures of odorants, often recognized as single entities due to odor blending (e.g., coffee). In contrast, we are also able to discriminate odors from complex mixtures (e.g., off-odors). Therefore, the olfactory system is able to engage either configural or elemental processes when confronted with mixtures. However, the rules that govern the invo...