A series of new tetrasubstituted imidazoles 2-phenyl-3-(1, 4, 5-triphenyl-1H-imidazol-2-yl)-1H-indole derivatives substituted with –F, Cl, Br, I,-OCH3 and -NHCOCH3 were synthesized using a multicomponent reaction. The compounds were obtained in good yields by easy workup and with high purity

In the first phase of this master’s thesis, an overview of different approaches involving artificial intelligence to support situation assessment is presented, discussing the potential and the limits of each approach. In particular, two key issues in the context of automated sea surveillance are addressed: identification of particular events and scenarios in the situation picture, and detection...

Practical synthesis of tetrasaccharide sulfates, 6((GlcNAc))-O-Su-SiaLe(X)-OCH(2)CH(2)CH(2)NH(2) and 6((Gal))-O-Su-SiaLe(X)-OCH(2)CH(2)CH(2)NH(2) (Su( )SO(3)H), selectin ligands, and leu- kocyte trafficking agents is presented. Both sulfates were synthesized starting from the same precursor, protected SiaLe(x), by the conventional procedures of carbohydrate chemistry. The sulfated SiaLe(x) deri...

Oriental cholangiohepatitis (OCH) is a disease characterized by intrabiliary pigment stone formation, resulting in recurrent bouts of cholangitis. OCH is found mostly in Southeast Asia but it is occasionally recognized in Western societies. OCH etiology is largely unknown. We report our experience with a patient who presented with acute cholecystitis. Following laparoscopic cholecystectomy, she...

Both Multiple Sclerosis (MS) and Guillan-Barré syndrome (GBS) are neurological inflammatory demyelinating autoimmune diseases, with a probable antibody contribution. Complement proteins in both MS and GBS does play a role in inflammation and demyelination at pathogenesis, according to earlier scientific evidence. The aim of this examination project work was to investigate systemic and intrathec...

BACKGROUND Preoperative oral carbohydrate (OCH) improves postoperative insulin resistance (PIR) and insulin sensitivity. However, the exact mechanisms involved in the improvement of PIR with respect to preoperative OCH are still not clear. The aim of this study was to investigate the involvement of preoperative OCH and PI3K/AKT/mTOR pathway in reducing PIR in rats. MATERIAL AND METHODS Forty ...

s of the EU life algae Programme Conference 2001. Länsstyrelsen iGöteborgs and Bohus län. Sida 53.Jenneborg, L-H. 1998. Marinbiologisk kontroll: Ålgräsvegetationen inom Göteborgskommun. Miljöförvaltningen Göteborgs stad. HydroGIS AB rapport 176. 10sidor.2000a. Ålgräsvegetationen i Göteborgs kustvattenområden. Miljö-förvaltningen Göteborgs stad rapport 2000:3. HydroGIS AB...

Grammar errors and context-sensitive spelling errors in texts written by second language learners are hard to detect automatically. We have used three different approaches for grammar checking: manually constructed error detection rules, statistical differences between correct and incorrect texts, and machine learning of specific error types. The three approaches have been evaluated using a cor...

Certain glycolipid Ags for Valpha14i NKT cells can direct the overall cytokine balance of the immune response. Th2-biasing OCH has a lower TCR avidity than the most potent agonist known, alpha-galactosylceramide. Although the CD1d-exposed portions of OCH and alpha-galactosylceramide are identical, structural analysis indicates that there are subtle CD1d conformational differences due to differe...

Sjukhusrelaterade infektioner är en vanlig orsak till dödlighet och lidande runt om i världen. Ett allt större intresse har visats detta ämnesområde och WHO har påpekat vikten av att jobba med dessa frågor. Problemet är störst på sjukhusens intensivvårdsavdelningar där de sjukaste patienterna vårdas. Förekomsten av bakterier som är resistenta mot ett eller flera antibiotika är också störst på d...