Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity . This periodicity was also observed in thin-section profiles of beta granules in intact cells . In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure . The presence of such a periodicity in t...

Electrophysiological studies have been performed on cultured neurons isolated from the fetal (or newborn) rat or mouse central nervous system (CNS) (Barker and Ransom, 1978a, b; Mathers and Barker, 1980). Recently, several reports have appeared describing the electrophysiologi cal properties of acutely dissociated neurons from the adult mammalian CNS (Kay and Wong, 1986; Kiskin et al. 1986a, b;...

Background: Endometriosis is the growth of endometrial cells outside the uterine cavity. It has been suggested that immune system plays important roles in both initiation and progression of the disease. Several studies have been shown that women with endometriosis diverge in their expression of different genes including heat-shock proteins, fibronectin, and neutrophil elastase, which might be i...