Background: Many reports are available about the increasing rate of mortality due to overuse of opioids. It has been suggested that sleep apnea can be a cause of mortality because of overuse of opioids. Opium use is common in Iran. This study aimed to assess the effect of opium on polysomnographic findings in opium addicts with sleep apnea syndrome. Materials and Methods: In this prospective ca...

Recognition and treatment of secondary causes of hypertension among patients with resistant hypertension may help to control blood pressure and reduce cardiovascular risk. However, there are no studies systematically evaluating secondary causes of hypertension according to the Seventh Joint National Committee. Consecutive patients with resistant hypertension were investigated for known causes o...

Obstructive sleep apnea hypopnea syndrome (OSAHS) is apnea and hypoventilation caused by upper airway collapse during sleep, accompanied by snoring, disrupted sleep structure, frequent occurrence of oxygen desaturation and daytime sleepiness [1,2]. OSAHS has a rather high prevalence and can cause systemic and multi-system damages. Hence, it has received increasing attention in recent years. The...

Aside surgical and orthodontic treatment and nocturnal ventilation, there are two types of treatment adapted for childhood obstructive sleep apnea-hypopnea syndrome (OSAHS): pharmacological treatment is reserved to non-severe OSAHS with no upper airway obstruction, because of limited efficacy; oro-myofacial rehabilitation is always associated to other therapeutic interventions.

Obstructive Sleep Apnea (OSA), a stoppage or partial stoppage of air flow during sleep has been gaining more attention as a Sleep Related Breathing Disorder. This treatable syndrome has many associated co-morbidities that can have severely detrimental effects on a person’s well being and general health. It has been estimated that 20% or more of the population suffers from some level of OSA, man...

OBJECTIVE To validate the pediatric obstructive sleep apnea screening tool for use in Brazil. MATERIALS AND METHODS The Brazilian version of this questionnaire, originally validated and tested in the United States, was developed as follows: (a) translation; (b) back-translation; (c) completion of the final version; (d) pre-testing. The questionnaire was applied prior to polysomnography to chi...

STUDY OBJECTIVE Sleep-disordered breathing (SDB) is a prevalent condition in children and is associated with increased cardiovascular morbidity. Circulating levels of C-reactive protein (CRP), a proinflammatory protein, are associated with increased risk for atherosclerosis. Plasma CRP levels in snoring children have yielded conflicting results, such that it remains unclear whether OSA is mecha...

OBJECTIVE To assess the relation between medications prescribed for chronic pain and sleep apnea. DESIGN An observational study of chronic pain patients on opioid therapy who received overnight polysomnographies. Generalized linear models determined whether a dose relation exists between methadone, nonmethadone opioids, and benzodiazepines and the indices measuring sleep apnea. SETTING A pr...