several modalities of drug administration have been investigated to improve bioavailability and to reduce 5-fu related toxicity. the aim of present study was to evaluate the effect of skimmed milk on the absorption and metabolism of 5-fu in rabbits, mice and dogs. it was further aimed to determine its route related toxicity in rabbits.    plasma concentration of both 5-fu and its metabolite 5-f...

introduction todays, the application of new methods for monitoring and online management of agricultural farms is necessary to increase quality and quantity of agricultural products. remote sensing is one of the technologies that can be used to monitor agricultural farms and natural resources. this technology is capable of detection and prediction of farm changes by application of satellite and...

effect of foliar spraying by humic acid on mineral leaf composition, yield and fruit quality of apple (malus domestica l. cv. ‘granny smith’) was studied. an experiment based on randomized complete design was conducted in khorramdare city of zanjan province. spraying of humic acid was conducted in four levels 0, 5, 10 and 15 mg/l on eight year-old ‘granny smith’ apples grafted on mm106 rootstoc...

organochlorine pesticides are as environmental pollutants which have a high half-life and transmit from food chain to human and cause side effects such as mutations in different genes and finally cancer. in this research, after sampling and quantitative and qualitative of organochlorine residue, biodegradation of alpha, beta and gamma hexachlorobenzene (linden), ddt, aldrin, dieldrin, endosulfa...

this qualitative study was conducted to identify the factors and barriers of entrepreneurship development from the perspective of iranian entrepreneurs. in terms of purpose, this study is applied- developmental and it is performed via descriptive phenomenological method. qualitative content analysis was used to collect the data. the study population comprised of recorded interviews with the ent...

evaluation of changes present in soil and water resources due to operation implement of floodwater spreading is necessary to assess their positive or negative resultant effect. rate of the internal sediment to diversion spreader channels, surface sedimentation and aggregation of the spreading field depth are most important effective attributes on the yield of floodwater spreading systems. these...

introduction prediction of thunderstorm is one of the most difficult issues in weather forecasting. deep convective clouds develop at small spatial and temporal dimensions about 1-10 km and 1-12 h. various thermodynamic parameters have been discovered over the past 40 years, according to data obtained by radiosounds. the capability of these indices in forecasting instability varies over time an...

theaim of the current study was to assess effects of different levels of origanum vulgare (0, 250, 500, 750 and 1000 mg/l) on kinetics of gas production, some ruminal digestion and fermentation parameters, methane production and also to determine its potential in controlling rumen acidosis using in vitro method in four separate phases. in the first phase, the asymptote of gas production (a) and...

the intensive use of antimicrobial agents worldwide for prophylactic and therapeutic purposes has been associated with increase of bacterial resistance in the exposed microbial environment. oxytetracycline is the most frequently used antibacterial in the cold water fish industry because of its broad spectrum of activity and low cost. aeromonas hydrophila and other motile aeromonads are among th...

background and objectives: the region of the experiment is located in golestan province, iran, with agriculture subject to various farming conditions (rain-fed and irrigation) and different levels of salinity (more than 38% of golestan’s total land area is salt-affected). the purpose of this study has been to evaluate the stress indices in the selection of tolerant wheat genotypes, not only for...