The new series of Schiff base were synthesized from 7-methyl-2-phenylimidazo[1,2-a]pyridin-3-amine condensed with different substituted aldehydes (4-Hydroxybenzaldehyde, Vanillin, 3-Nitrobenzaldyde, 4Nitrobenzaldehyde)in presence of catalytic quantities of acetic acid. So the structure offers for this synthesis well coincide with the results obtained bydifferent spectroscopic techniques (IR, 1 ...

Vanillyl-alcohol oxidase is a flavoprotein containing a covalent flavin that catalyzes the oxidation of 4-(methoxymethyl)phenol to 4-hydroxybenzaldehyde. The reaction proceeds through the formation of a p-quinone methide intermediate, after which, water addition takes place. Asp-170, located near the N5-atom of the flavin, has been proposed to act as an active site base. To test this hypothesis...

During the development of an assay for the metanephrines (m 0 -methylepinephrine and m 0 -methylnorepinephrine) in human urine (I), another compound was detected which had similar chemical and chromatographic properties. Like the metanephrines, it was adsorbed onto a weak cation exchange resin, and upon treatment with periodate it yielded a product which absorbed ultraviolet light. The identifi...

Laccasc (benzenediol: oxygen oxidoreductase, EC 1.1O.3.2) has been found in some fungal strains belonging to various classes.i) The enzyme generally catalyzes the removal of hydrogen from phenolic hydroxyl groups or aromatic amino groups using molecular oxygcn as a primary electron acceptor to give radicals, which undergo free-radical additions and related reactions to give various products.2-s...

Ti(III),Mn(III) & Co(III) complexes of schiff bases derived from condensation reaction of 3-(2amino-4-thiazolyl)coumarin with 2-hydroxybenzaldehyde,2-hydroxy-3-methoxy benzaldehyde and 2hydroxy-1-napthaldehyde have been prepared and characterised. All the three ligands function as uninegative bidentate coordinating ligands with metal ions through phenolic oxygen and azomethine nitrogen. The com...

1,2-bis-(4-Hydroxy-3-methoxyphenyl)-3-hydroxypropan1-one (evafolin B, 1), 1-(4-hydroxy-3-methoxyphenyl)3-hydroxypropan-1-one (2), were isolated for the first time from the genus Schisandra, along with abscisic acid (3), 4-hydroxybenzaldehyde (4), 4-hydroxybenzoic acid (5), methyl 4-hydroxybenzoate (6), methyl 3,4-dihydroxybenzoate (7), and vanillic acid (8). All the compounds were evaluated for...

In this study, the characterization of chemical constituents and biological activity of the roots of Taraxacum coreanum (Asteraceae) was attempted. Phytochemical investigation of the roots of T. coreanum led to the isolation of two new inositol derivatives, taraxinositols A (1) and B (2), and a new phenolic compound, taraxinol (16), together with twenty known compounds including four inositol d...

Safflower injection is well-known as a traditional Chinese medicine used to improve the blood circulation. In this study, seven safflower injection samples from different companies were evaluated for their in vitro anticoagulant activity by measuring their activated partial thromboplastin time (APTT) and prothrombin time (PT) against human plasma. The screening results suggested that the safflo...