Giant pituitary adenomas are uncommonly large tumors, greater than 4 cm in size that can produces endocrine symptoms, visual loss and cranial nerve palsies. We report the rare occurrence of seesaw nystagmus as the presenting sign of giant pituitary adenoma. A 50-year-old man presented with headache associated with visual loss and seesaw nystagmus. Perimetry revealed bitemporal hemianopia and ma...

Direct current electronystagmographic recordings of spontaneous nystagmus in light, in darkness, and with eye closure have been carried out on (a) 33 patients with acoustic neurinomata pressing on the brain stem, and (b) 10 patients with lesions involving the brain stem at a high level. Patterns of response characteristics of each group have been identified in 21 out of 28 cases of group a, the...

Thirty seven patients with pendular nystagmus due to multiple sclerosis were reviewed. Most developed nystagmus later in a progressive phase of the disease. All had cerebellar signs on examination and evidence of optic neuropathy. MRI in eight patients showed cerebellar or brainstem lesions in seven; the most consistent finding was a lesion in the dorsal pontine tegmentum. Dissociated nystagmus...