نتایج جستجو برای: nucleotide
تعداد نتایج: 130909 فیلتر نتایج به سال:
Background and Aims: Ficolins are proteins that bind to carbohydrates, act as opsonins and play an important role in innate immunity. Polymorphism in ficolin-3 gene (FCN3) can lead to complement deficiency and increase the risk of some disorders such as diabetes. The aim of this study was to investigate the frequency of FCN3+1637delC as a single nucleotide polymorphism in this gene in healthy a...
Abstract Single-nucleotide variants account for about half of known pathogenic genetic in human. Genome editing strategies by reversing point mutations with minimum side effects have great therapeutic potential and are now being actively pursued. The emerge precise efficient genome such as base prime provide powerful tools nucleotide conversion without inducing double-stranded DNA breaks (DSBs)...
The Single Nucleotide Polymorphisms (SNP) Discovery on Transcriptome of Pure Sistani and Cross-Breeding Holstein, Simmental Monte Billiard Bulls
The DNA barcode of Bruchidius varius collected from Dilek Peninsula and Büyük Menderes Delta National Park (DPNP) in Aydın province Turkey is given for the first time. As barcode, mitochondrial cytochrome c oxidase subunit I (COI) with a length approximately 628 bp sequenced an illustrative presented along nucleotide composition target gene location. Nucleotide sequence includes 38.63% T, 27.98...
Introduction: Hepatitis B virus (HBV) infection is a major health problem worldwide and may lead to serious clinical complications, including chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. The host’s genetic background in immune system genes is a crucial etiologic factor in progression of HBV infection to chronic disease or clearance of the virus from the body. Interleu...
Background and purpose: Hemophilia is a hereditary X-linked disorder. Females are carriers and males have the disorder. Hemophilia A is caused by deficiency in the production of factor VIII. In some hemophilia patients, inhibitors including IgG1 and IgG4 antibodies are expressed against this factor. These inhibitors interact with factor VIII and suppress its function. The current study aimed at...
Background and purpose: Cytokines are a group of endogenous proteins which play an influential role in regulating the inflammatory responses and defeating infectious diseases. Elevated levels of proinflammatory cytokines and their receptors are usually observed in association with immune responses against viral infections such as hepatitis B virus (HBV) infection. IL 12 and its receptor play an...
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