Nu-3 [butyl-phosphate-5'-thymidine-3'-phosphate-butyl] is a modified nucleotide that has been shown to have antimicrobial activity against a range of bacteria including Pseudomonas aeruginosa. However, data on the toxicological profile of Nu-3 are still lacking. In the present study, the toxicity of Nu-3 was evaluated by the following studies: acute oral toxicity, dermal and mucous membrane irr...

Nu-Lure and other protein solutions were presented to Anastrepha suspensa in J-tubes and consumption was quantified spectrophotometrically. In choice comparisons, flies consumed more or equal water compared to Nu-Lure and more Nu-Lure compared to Bragg’s Liquid Aminos, corn steep liquor, NZ case, pepticase, Solulys, soy hydrolysate, Torula yeast, whey, and yeast enzymatic hydrolysate. Consumpti...

We study the voter model on heterogeneous graphs. We exploit the nonconservation of the magnetization to characterize how consensus is reached. For a network of N nodes with an arbitrary but uncorrelated degree distribution, the mean time to reach consensus T(N) scales as Nmu(2)1/mu(2), where mu(k) is the kth moment of the degree distribution. For a power-law degree distribution n(k) approximat...

In this paper we introduce derivations in Krasner hyperrings and derive some basic properties of derivations. We also prove that for a strongly differential hyperring $R$ and for any strongly differential hyperideal $I$ of $R,$ the factor hyperring $R/I$ is a strongly differential hyperring. Further we prove that a map $d: R rightarrow R$ is a derivation of a hyperring $R$ if and only if the in...

BACKGROUND AND OBJECTIVES The aim of this study was to validate the Portuguese version of the Nursing Delirium Screening Scale (Nu-DESC) for use in critical care settings. METHODS We simultaneously and independently evaluated all postoperative patients admitted to a surgical Intensive Care Unit (SICU) over a 1-month period for delirium, using the Portuguese versions of both the Nu-DESC and th...

Anisotropic charge transport is observed in a two-dimensional (2D) hole system in a perpendicular magnetic field at filling factors nu=7/2, nu=11/2, and nu=13/2 at low temperature. In stark contrast, the transport at nu=9/2 is isotropic for all temperatures. Isotropic hole transport at nu=7/2 is restored for sufficiently low 2D densities or an asymmetric confining potential. The density and sym...

Colony counts, scanning electron microscopy, and light microscopy were used to assess the capacity of Candida albicans to colonize (naturally) and infect the alimentary tract of adult and neonatal (athymic [nu/nu] or heterozygous [+/nu] littermates) germfree BALB/c mice. When exposed to yeast-phase C. albicans, the alimentary tract of adult germfree mice (nu/nu or +/nu) is quickly (within 24 to...

CD45 is a membrane-associated tyrosine phosphatase that dephosphorylates Src family kinases and Janus kinases (JAKs). To clarify the role of CD45 in hematopoietic differentiation, we examined the effects of anti-CD45 monoclonal antibody NU-L(PAN) on the proliferation and differentiation of umbilical cord blood CD34(+) cells. NU-L(PAN) showed a prominent inhibition of the proliferation of CD34(+...