BACKGROUND Bleomycin is a cytotoxic drug used in treatment of Germ Cell Tumours (GCTs) and is associated with pulmonary toxicity. Bleomycin pulmonary toxicity (BPT) manifests predominantly as pulmonary fibrosis, organising pneumonia (OP) or Nonspecific Interstitial Pneumonitis (NSIP). Our objectives were to determine the incidence of BPT, describe the common HRCT patterns of pulmonary toxicity ...

To describe the computed tomography (CT) features of chemotherapy-induced interstitial pneumonitis (CIIP) with longitudinal follow-up.The study was approved by the local ethics committee. One hundred consecutive patients with CIIP between May 2005 and March 2015 were retrospectively enrolled. The initial CT was reviewed by 2 independent chest radiologists and categorized into 1 of 4 CT patterns...

There has been significant interest in nanophotonics for global on-chip communication and for inter-socket communication between processors and/or main memory. Our goal in this short paper is to motivate future research on nanophotonic systemin-package (NSiP): an integration strategy that uses CMOScompatible nanophotonic devices to implement an efficient package-level network for high-performan...

Background: The aim of the study was to evaluate radiographic features systemic sclerosis-associated interstitial lung disease. Patients and methods: 116 patients with disease (SSc-ILD) from 2010 2019 comprised our retrospective study. All were subject high resolution computed tomography (HRCT). ILD patterns classified into 7 as IIPs analyzed pathology. We chose two staging method semi-quantita...

PURPOSE To determine high resolution computed tomography (HRCT) patterns and pulmonary function indices which are associated with increased mortality in patients with connective tissue disease related fibrotic lung disease (CTD-FLD). METHODS HRCTs from 168 patients with CTD-FLD were scored by 2 observers for a variety of HRCT patterns and traction bronchiectasis. A radiological diagnosis of u...

Interstitial lung disease compatible with idiopathic pulmonary fibrosis (IPF) developed in 19 previously healthy patients. Although interstitial and/or honeycomb parenchymal fibrosis was present in all, there were patchy areas of paucicellular septal capillary injury along with corroborative direct immunofluorescent evidence of a humorally mediated microvascular injury syndrome. Significantly e...

Connectedness among animals in separate flocks reduces the risk of biased comparisons when selecting across flocks on EBV. The objective in this study was to assess levels of connectedness in the genetic evaluation of weaning weight among Targhee and Suffolk flocks participating in the US National Sheep Improvement Program (NSIP). Among flocks currently participating in the NSIP, a total of 25,...