This work illustrates a comparative study on the applicability of the basic heterogeneous calcium oxide catalyst prepared from waste mollusks and crabs shells (MS and CS, resp.) in the transesterification of waste cooking oil collected from seafood restaurants with methanol for production of biodiesel. Response surface methodology RSM based on D-optimal deign of experiments was employed to stud...

It is well established that the performance of lipase B from Candida antarctica (CALB) as catalyst for esterification reactions may be improved by the use of ultrasound technology or by its immobilization on styrene-divinylbenzene beads (MCI-CALB). The present research evaluated the synthesis of butyl acetate using MCI-CALB under ultrasonic energy, comparing the results against those obtained u...

Kinetic resolution of 1-phenyl-2-propyn-1-ol, an important chiral synthon, was studied through trans-esterification with acyl acetate to investigate synergism between microwave irradiation and enzyme catalysis. Lipases from different microbial origins were employed for the kinetic resolution of (R/S)-1-phenyl-2-propyn-1-ol, among which Candida antarctica lipase B, immobilized on acrylic resin (...

The enzymatic degradation of chemically synthesized typical biodegradable plastics, such as poly(R,S-3-hydroxybutanoate), poly(3caprolactone) and poly(butylene adipate), into reactive cyclic oligomers under the continuous flow of supercritical or subcritical carbon dioxide (scCO2) with toluene through an enzyme column was studied with reference to chemical recycling. It was confirmed that all t...

Enantioenriched promethazine and ethopropazine were synthesized through a simple and straightforward four-step chemoenzymatic route. The central chiral building block, 1-(10H-phenothiazin-10-yl)propan-2-ol, was obtained via a lipase-mediated kinetic resolution protocol, which furnished both enantiomeric forms, with superb enantioselectivity (up to E = 844), from the racemate. Novozym 435 and Li...

Polycondensation in batch is the classical way to produce polyesters. However, this method requires harsh conditions reach high conversions and drive equilibrium of reaction forward. In order controlled polymers a greener way, we worked on enzymatic ring opening polymerization (e-ROP) lactones using CALB lipase immobilized porous beads (Novozym® 435) as catalyst 3-phenyl-1-propanol (PP) initiat...

The lipid products that consist of structured lipids rich in palmitic acid (16:0) at the sn-2 position triacylglycerol (TAG) and low-unsaturated fatty acids (FAs) (LUFAs), such as oleic acid; 18:1 linoleic 18:2 sn-1(3) positions, are useful intermediates for manufacturing human milk fat substitute (HMFS), which contains functional components. In this study, HMFS intermediate (HMFS-IM) was enzym...

Poly(butylene succinate) (PBS) is a bio-based and biodegradable polyester that can be used in numerous applications, ranging from clothing to food packaging the car industry biomedical sector (e.g., drug release systems). The conventional polymerization method of PBS requires presence metal-based transesterification catalysts titanium-based catalysts) high reaction temperatures (T > 150 °C)....

Feeding behaviour is crucial for the survival of an organism and is regulated by different brain circuits. Among these circuits the mesolimbic dopamine (DA) system is implicated in the anticipation and motivation for food rewards. This system consists of the dopaminergic neurons in the ventral tegmental area (VTA), and their projections to different cortico-limbic structures such as the nucleus...