Highlights: The modified Millard technique, including the Tennison triangular flap, is effective in preventing vermillion notching and reducing scar complications cleft lip repairs. technique addresses concerns related to compromised tissue nostril deformities, leading improved appearance functionality. Scar thinning techniques separate nasoraphy contribute enhanced aesthetics optimal healing A...

Notch receptors play an essential role in the regulation of central cellular processes during embryonic and postnatal development. The mammalian genome encodes for four Notch paralogs (Notch 1-4), which are activated by three Delta-like (Dll1/3/4) and two Serrate-like (Jagged1/2) ligands. Further, non-canonical Notch ligands such as epidermal growth factor like protein 7 (EGFL7) have been ident...