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BACKGROUND Carbon monoxide (CO) was previously only considered as a highly toxic pollutant since it binds to hemoglobin with high affinity. Recently, however, it has been recognized as a signaling molecule with regulatory roles in many physiological and pathophysiological processes within the cardiovascular system. The aim of this study was to clarify the behavior of CO in patients with acute c...

Some recent studies show an association between a functional polymorphism of BDNF gene (Val66Met) and the susceptibility to nicotine dependence and we hypothesized that this polymorphism was associated with smoking in both schizophrenia patients and healthy controls. The BDNF Val66Met gene polymorphism was genotyped in 690 chronic male schizophrenia patients (smoker/nonsmoker = 522/169) and 628...

275 J .W., a healthy 50-year-old critical care nurse with no significant medical history, was in her second marriage, postmenopausal, a nonsmoker with remote history of smoking for about one year, and reported occasional alcohol use. She presented to her primary care physician with complaints of an 18-month history of sporadic bright red blood per rectum, particularly when straining to have a b...

Objective: To determine the frequency of periodontal pocket associated with full coverage fixed prostheses in patients coming to Rehmat Memorial Dental Teaching Hospital, Abbottabad. Material and methods: This cross-sectional study was conducted on 116 participants both genders, age 30 60 years, systemically healthy, nonsmoker root canal treated abutment teeth having for at least one year. The ...