Background: Skin cancer is one of the most common forms of cancer in the world and melanoma is the deadliest type of skin cancer. Both melanoma and melanocytic nevi begin in melanocytes (cells that produce melanin). However, melanocytic nevi are benign whereas melanoma is malignant. This work proposes a deep learning model for classification of these two lesions.    Methods: In this analytic s...

BACKGROUND The aim of this study was to assess the content validity of a questionnaire to measure melanoma risk, knowledge and protective behaviour in a convenience sample of Scots and Australians. Australia has the highest melanoma incidence worldwide but has developed a culture of skin cancer avoidance with a long history of skin cancer primary prevention campaigns of proven effectiveness. Sc...

Cancer-associated fibroblasts (CAFs) play a key role in disease progression and treatment outcome. We used single-cell transcriptomics, CNV analysis, andin situ stainings to elucidate the yet unresolved intra-tumoral CAF heterogeneity melanoma non-melanoma skin cancer (basal squamous cell carcinoma, BCC SCC). identified three major subtypes, with their presence being indicative for tumor malign...

this study was carried out as a pilot project in imam-khotneini, a teaching general hospital mainly dealing with cases of reconstructive surgery. the age of onset! geographical distribution, histologic type and other features ofskin cancer in iran were determined. the most coftutloll neoplasm in both sexes was bee the age group 0/65 and over had higher rate of acquired skin cancers. east aiarbu...

Skin cancer incidence has increased exponentially over the last three decades. In 2008 skin cancer caused 2280 deaths in the UK, with 2067 due to malignant melanoma. Early diagnosis can prevent mortality, however, conventional treatment requires multiple procedures and increasing treatment times. Second harmonic generation (SHG) imaging could offer diagnosis and demarcation of melanoma borders ...

Skin cancer is a worldwide, emerging clinical need in the elderly white population, with a steady increase in incidence rates, morbidity and related medical costs. Skin cancer is a heterogeneous group of cancers comprising cutaneous melanoma and non-melanoma skin cancers (NMSC), which predominantly affect elderly patients, aged older than 65 years. Melanoma has distinct clinical presentations i...

Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA sequencing (RNA-seq) to analyse the transcriptome of a panel of non-melanoma skin cancer lesions, identifying genes that are consistently expressed across all samples. Genes encoding ribosomal protei...

Purpose: Given rising rates of deadly melanoma skin cancer in Hispanics, the study objective was to examine skin cancer-related risk reduction behaviors and beliefs to dictate content for culturally targeted skin cancer prevention strategies for Hispanics. Methods/Data Source: An anonymous survey was administered to waiting room volunteers in a primary care facility in Albuquerque, New Mexico t...

Brøndum-Jacobsen et al. recently published in this journal analyses of Danish register data concerning myocardial infarction, hip fracture and death from any cause, using incidence of skin cancer as indicator of high exposure to sunlight. The basic idea in the paper is that those who get a skin cancer diagnosis at any age are supposed to have been more exposed to the sun during their life than ...