The title salts, C8H13N4 (+)·Cl(-), (I), and C8H13N4 (+)·NO3 (-), (II), contain linked pyridinium-piperazine heterocycles. In both salts, the piperazine ring adopts a chair conformation with protonation at the N atom not linked to the other ring. In the crystal of (I), weak N-H⋯Cl inter-actions are observed, leading to zigzag chains along [100]. In the crystal of (II), both H atoms on the NH2 (...

Present work is aimed at assessing Water Quality Index (WQI) for groundwater of Upper Pincha Basin, Chittoor District, Andhra Pradesh. This has been carried out by collecting groundwater samples and subjecting them to comprehensive physico-chemical analysis. Results obtained were compared with standard values recommended by WHO for drinking and public health. For computing WQI, eleven parameter...

In the title mol-ecular salt, C6H10N2 (2+)·NO3 (-)·Cl(-), the complete cation is generated by a crystallographic mirror plane. The complete nitrate ion is also generated by reflection, with the N atom and one O atom lying on the mirror plane; the chloride ion also lies on the reflection plane. In the crystal, the components are linked by N-H⋯Cl and N-H⋯(N,O) hydrogen bonds, forming (001) layers...

A series of cyclic 2,6-bis-(1,2,3-triazolyl)-pyridine anion receptors with thiourea functionalities were synthesized by click reaction of 2,6-diazidopyridine with protected propargylamine followed by condensation of a bisthiocyanate derivative with a series of diamines. Their chloride binding affinities as well as their transport properties in POPC bilayers were examined. These receptors were f...

Several members of the SLC26 gene family have highly-restricted expression patterns in the auditory and vestibular periphery and mutations in mice of at least two of these (SLC26A4 and SLC26A5) lead to deficits in hearing and/or balance. A previous report pointed to SLC26A7 as a candidate gene important for cochlear function. In the present study, inner ears were assayed by immunostaining for S...

Two new complexes, [Cu(dimpyr)2(H2O)2](NO3)2.2H2O (1) and (Hamdimpy)2[CoCl4].H2O (2), with the monodentate ligand 2-amino-6-methylpyrimidin-4-(1H)-one (dimpyr) countercation 4-amino-2,6-dimetylpyrimidium (Hamdimpy), respectively, were prepared characterized by single crystal X-ray diffraction, elemental analysis IR spectroscopy. In (1), Cu(II) cation is tetracoordinated, in a square plan fashio...

The structure of a salt of diprotonated endo-3-amino-tropane crystallized with a copper(II) anionic cluster is reported, viz. (C8H18N2)[CuCl3(NO3)(H2O)]. Neither ion in the salt has been structurally characterized previously. In the crystal, the ions pack together to form a three-dimensional structure held together by a network of inter-molecular N-H⋯O, O-H⋯Cl and N-H⋯Cl hydrogen-bonding inter-...

The inner membrane of liver and heart mitochondria possesses an anion uniport pathway, known as the inner membrane anion channel (IMAC). IMAC is inhibited by matrix Mg2+, matrix H+, N,N'-dicyclohexycarbodiimide, mercurials and amphiphilic amines such as propranolol. Most of these agents react with a number of different mitochondrial proteins and, therefore, more selective inhibitors have been s...

Acid rain still poses a global problem today, exerting many adverse effects on man, animal, and materials. As its research question, the present study tries to find out whether or not acid rains exist in Akure, Nigeria. For so doing, it determines physico-chemical properties of rain water samples, namely pH, temp, Electrical Conductivity (EC), TDS, acidity, SO4-, NO2-, Cl-, and Free CO2. Accord...

Hypo-osmotic swelling of carp red blood cells (RBCs) induced a regulatory volume decrease (RVD), which restored the original cell volume within 140 min in oxygenated RBCs, whereas volume recovery was incomplete in deoxygenated RBCs. The complete RVD in oxygenated RBCs resulted from a sustained volume-activated release of K+, Cl- and amino acids (AAs). In the absence of ouabain, the cells also l...