evidence supports the involvement of nitric oxide (no) in a varity of male reproductive processes such as spermatogenesis, spermiogenesis, sperm motion, sperm metabolism and sperm capacitation. however, low concentration of no is essential in biology and physiology of spermatozoa, but high amounts of no is toxic and has negative effects on sperm functions. on the other hand, it is established t...

background: hawthorn species decreases blood pressure and relaxes precontracted vessels. this study aimed at examining the antihypertensive effect and related mechanisms of hydroalcoholic extract of crataegus azarolus subspecies aronia fruit in rats with renovascular hypertension. methods: six groups of male sprague-dawley rats, each containing 6 to 8 rats, were studied. the groups comprised of...

background: in some disorders such as diabetes mellitus patients can display depressive symptoms. metformin is among the first-line treatments for management of the type 2 diabetes mellitus which may have some anti-depressant effect. objective: current investigation was performed to examine the anti-depressant effects of metformin and the involvement of nitric oxide (no) in this way, in an expe...

background and objective: nitric oxide (no) plays a role in thermoregulation and growth of protozoa. this work aimed to add the molecule no in physiology of protozoa in contact with abused narcotic substances. materials and methods: a sedative drug, morphine, was infused into a cell chamber containing paramecia . the cell response to the drug was recorded promptly after drug infusion using a po...

Abstract The metal retention behaviors of several simulated radiolysis products on zirconium were investigated, and it was found that acid phosphate product HDEHP has the greatest effect. effects extraction nitric concentration, temperature behavior also investigated. results showed forms complexes with resulting in organic phase. Nitric concentration change morphology thus affecting behavior. ...

Tetrathiepin, Pentathiocin. Tetrathiepin-S-oxide, Tetrathiocin-S-oxide, Platinum C om plexes 5H -B en zo[f]-l,2 ,3 ,4-tetrath iep in-l-oxide 5 and l,2-B enzo-4,5.6,7-tetrath iocin-4-oxide 6 have been prepared by oxidation of the corresponding tetrasulfides 3 and 4, respectively using w C P B A in dichlorom ethane. The unstable bright yellow crystals o f 5 were characterized by an X-ray structur...

background: skin flap grafting is a popular approach for reconstruction of critical skin and underlying soft tissue injuries. in a previous study, we demonstrated the beneficial effects of two 5α-reductase inhibitors, azelaic acid and finasteride, on tissue survival in a rat model of skin flap grafting. in the current study, we investigated the involvement of nitric oxide and inducible nitric o...

the mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. in this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. the variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. different concentrations of lead acetate (10-9 to 10-6 m), wre added t...

objective(s) the fractions of candida albicans have been used as an immunomodulator. the present work assessed the effect of different fractions of c. albicans on nitric oxide (no) production by mice peritoneal macrophages. materials and methods cell wall and cytoplasmic fractions of c. albicans atcc 10321 strain were extracted. mice peritoneal macrophages were purified and cultured. different ...

introduction: different vasoactive factors can modulate cardiovascular adaptation to hemorrhagic shock including nitric oxide (no). in this study we investigated the effect of  the no synthase inhibitor for treatment of  decompensated hemorrhagic shock in normotensive and hypertensive rats. methods: twenty‑four male wistar rats were divided into two groups: the normotensive and hypertensive gro...