Materials Tris[2-(dimethylamino)ethyl]amine (Me6TREN) was prepared as described in the literature. Oligo (ethylene glycol) methacrylate with an average Mn of 500 g/mol (OEGMA-OH) was purchased from Sigma-Aldrich and filtered through basic alumina to remove stabilizers. N-Isopropylacrylamide (NIPAM) was recrystallized from cyclohexane before use. Cuprous bromide (CuBr) and cuprous chloride (CuCl...

In this work, we compare the properties of smart homopolymer microgels based on N-n-propylacrylamide (NNPAM), N-isopropylacrylamide (NIPAM) and N-isopropylmethacrylamide (NIPMAM) synthesized under identical conditions. The particles are studied with respect to size, morphology, and swelling behavior using scanning electron and scanning force microscopy. In addition, light scattering techniques ...

Two distinct uniform hybrid particles, with similar hydrodynamic diameters and comparable zeta potentials, were prepared by copolymerizing N-isopropylacrylamide (NIPAM) and styrene. These particles differed in their styrene to NIPAM (S/N) mass ratios of 1 and 8 and are referred to as S/N 1 and S/N 8, respectively. Particle S/N 1 exhibited a typical behavior of soft particles; that is, the parti...

Dual thermoand pH-responsive comb-type grafted hydrogels of poly(N,N-dimethy laminoethyl methacrylate) (PDMAEMA) and poly(N-isopropylacrylamide) (PNIPAM) with reversed network-graft architectures were synthesized by the combination of atom transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT) polymerization and click chemistry. Two kinds of macro-cross-...

Abstract Adjuvants drive the efficacy of many vaccines, however, they also elicit undesirable inflammation which is commonly pyrogenic resulting in local or systemic increases temperature. Based on this, we envisioned that inversely coupling adjuvant potency to small (~2 °C) temperature changes could be a uniquely effective approach balance while maintaining safety and tolerability. Here report...

Abstract In order to study the distribution of ions around a thermo-responsive charged nanogel particle in an electrolyte media we use coarse-grained Molecular Dynamics (MD) simulations creation new model was needed, so that created and works but there are many things might consider it. We just getting same radius gyration others models to.