نتایج جستجو برای: nicotinic acetylcholine receptor
تعداد نتایج: 607747 فیلتر نتایج به سال:
Exogenous application of acetylcholine elicits inward currents in hippocampal interneurons that are mediated via a-bungarotoxin-sensitive nicotinic acetylcholine receptors, but synaptic responses mediated via such receptors have never been reported in mammalian brain. In the present study, EPSCs were evoked in hippocampal interneurons in rat brain slices by electrical stimulation and were recor...
Exogenous application of acetylcholine elicits inward currents in hippocampal interneurons that are mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors, but synaptic responses mediated via such receptors have never been reported in mammalian brain. In the present study, EPSCs were evoked in hippocampal interneurons in rat brain slices by electrical stimulation and were r...
Nicotinic acetylcholine receptors are found in microvascular endothelial cells. To reveal the functional role in cerebral angiogenic processes, we studied the nicotinic modulation of proliferation activity in cultured bovine and porcine cerebral microvascular endothelial cells. The proliferation activity was determined by an increase in the number of cells present in culture dishes. When the bo...
A high resolution structure of -conotoxin EI has been determined by H NMR spectroscopy and molecular modeling. -Conotoxin EI has the same disulfide framework as 4/7 conotoxins targeting neuronal nicotinic acetylcholine receptors but antagonizes the neuromuscular receptor as do the 3/5 and A conotoxins. The unique binding preference of -conotoxin EI to the 1/ subunit interface of Torpedo neuromu...
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