Objective(s): This study investigated the possible effects of low (3 mg/kg) and high (6 mg/kg) doses of nicotine on the skeletal development of rat fetuses by the double staining method and the protective role of melatonin (10 mg/kg) against these effects.Materials and Methods: Eighteen adult female Wistar-Albino rats were divided into six groups (n=3, each) as control, low-dose nicotine, high-...

Objective(s): Smoking opium/cigarette is a global health concern. The aim of this study was to examine learning and memory of rat male offsprings whose mothers had been exposed to either opium or morphine with nicotine during pregnancy. Materials and Methods: Wistar rats were used for the experiments. In the female rats, opium, morphine and nicotine dependencies were induced by daily injection...

BACKGROUND: Nicotiana tobacco contains large amounts of alkaloid nicotine. Tobacco plant is used for smoking and causes many health problems since it is high in nicotine which is one of the widely-recognized toxic compounds with serious side effects for different body organs. Reducing nicotine content of this plant is a way to reduce its health hazards in cigarette smokers. Utilizing the new ...

Background: Nicotine is a toxic compound in the cigarette smoke and has destructive effects on various human organs. Astaxanthin is a carotenoid with high antioxidant property. In this study, we investigated the protective effects of astaxanthin against nicotine-induced toxicity in mice testes. Methods: Forty-two inbred balb/c male mice were divided into six groups:Group 1, received 1 ml norma...

Cigarette smokers are generally known to gain weight after quitting smoking, and such weight gain is thought to contribute to the worsening of glucose tolerance. While smoking cessation therapy such as nicotine replacement is useful to minimize post-cessation weight gain, substantial gain occurs even during the therapy. The purpose of the present study was to identify factors associated with we...

background: infertility is common among couples of child-bearing age and ap-proximately half of known causes of primary infertility are attributable to male factor. it is still unclear whether the injurious effects of cigarette smoking on sperm characteristics and infertility are due to nicotine. therefore, the present study investigated the effects of orally administered of nicotine on sperm c...

Nicotine transdermal systems are being used as an aid to smoking cessation programs. As the kinetics of nicotine delivery is important in success of a smoking cessation program, rapid and high input of nicotine is required, which is not possible by passive methods and requires enhancement strategies such as iontophoresis. Iontophoretic permeation, of nicotine looks promising, based on published...

Electro-polymerized PEDOT film on a graphene-modified electrode is demonstrated as selective electrochemical nicotine sensor. Nicotine was detected with high selectivity and real sample analysis carried out.