More effective vaccines are needed to control avian diseases. The use of chicken interferon gamma (chIFNγ) during vaccination is a potentially important but controversial approach that may improve the immune response to antigens. In the present study, three different systems to co-deliver chIFNγ with Newcastle disease virus (NDV) antigens were evaluated for their ability to enhance the avian im...

Newcastle disease virus (NDV) is the causative agent of an economically important disease, which affects all species of birds worldwide. Current vaccination programs for NDV include the use of either low-virulent live-virus vaccines or inactivated vaccines to induce protective immunity while producing minimal adverse effects in birds. In order to further characterize the immune response elicite...

increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific immune responses of birds by the fast establishment of a beneficial microflora and immune stimulator factors to guarantee healthy and low-price products. during this study, 192 one-day-old broiler chicks (ross-380) in four groups with three replica...

The present study was designed to investigate effects of Lisovit (Biomin, Austria) on the immune system of broiler chickens. For this purpose, 270 (day-old) broiler chicks were randomly divided into three groups A, B and C of 90 birds each. The birds were vaccinated against Newcastle Disease (ND) on day 3 (intraocular) and day 18 (drinking water) of age and against Infectious Bursal Disease (IB...

an experiment was conducted to evaluate the effects of high dietary levels of selenium (as sodium selenite) and copper (as copper sulphate) on growth performance, serum biochemical parameters and antibody production against newcastle disease vaccine (ndv) virus in broiler chickens. a total of 160 ross 308 unsexed day old broiler chickens were randomly allocated into four treatment groups (n=40 ...

despite routine vaccination programs against newcastle disease (nd), sporadic cases have occasionally occurred that remain a constant threat to commercial poultry. ten isolates of newcastle disease viruses (ndv) from infected broiler chicken cases were obtained from various locations in fars province during 2009-2011 and genetically analyzed using reverse transcription polymerase chain reaction...

The interrelationships of the cellular receptors and the hemagglutinin inhibitors of a new strain of virus (1233) to members of the mumps-Newcastle disease-influenza group have been investigated. It was found that strain. 1233 does not destroy the receptors or inhibitors of the other group, nor does the latter destroy 1233 receptors or inhibitor. The sole exception to this statement was a moder...

This paper briefly reviews the advantages and limitations of the different vaccines available for use against Newcastle disease in village chickens. Inactivated vaccines give very good immunity without vaccinal reactions and have been widely used, but are relatively expensive and require training to apply. Live vaccines are easy to apply and relatively inexpensive, and give moderately good immu...

Vaccination against Newcastle disease (ND), a devastating viral of chickens, is often hampered by thermal inactivation the live vaccines, in particular tropical and hot climate conditions. In past, “thermostable” vaccine strains (I-2) were proposed to overcome this problem but previous comparative studies did not include formulation-specific factors commercial vaccines. current study, we aimed ...