recent studies have established that sex hormones directly or indirectly affect t and b cells and macrophages by manipulating the production of cytokines. in this study the possibility of the effect of 5a-dht on macrophage (mφ) nitric oxide (no) release via interleukin-l, 6 (ll-1β, il-6) or tumor necrosis factor-a (tnfα) was investigated. the endogenous cytokines il-1β, il-6 and tnf-α were neut...

Background Platelets contain several factors that inhibit heparin. This study was designed to assess the heparinneutralizing activity present in acute, platelet-rich arterial thrombi formed at sites of arterial injury in animals. Methods and Results Platelet-rich thrombi (n=3) were induced in pig coronary arteries by balloon catheter-mediated arterial injury. Soluble extracts were prepared from...

Strategies are needed for human immunodeficiency virus type 1 vaccine development that improves the neutralizing antibody response against primary isolates of the virus. Here we examined recombinant DNA priming followed by subunit protein boosting as a strategy to generate neutralizing antibodies. Both plasmid-based and recombinant protein envelope (Env) glycoprotein immunogens were derived fro...

The local secretory immune mechanism in infants with cytomegalovirus infection was studied by a measurement of neutralizing antibody in saliva. Neutralizing antibodies were determined by the microculture plaque assay in 65 saliva specimens including 54 samples from cytomegalovirus-infected subjects and 11 from seronegative controls. In addition, cytomegalovirus isolation from saliva or urine or...

a micro neutralization test was used for the detection and evaluation of mumps neutralizing antibodies. a total of 1037 blood samples from selected groups of students aged 7 to 22 years in south and east of tehran, 139 blood samples from the umbilical cords of pregnant women at two tehran hospitals at delivery time, and 190 samples from children under five years of age who were living in two vi...

Abstract Corrosion is considered one of the major problems that affect flow assurance during hydrocarbon production. This irreversible phenomenon has ability to cause serious material failure in oil and gas industry. Consequently, heavy capital operational costs are required prevent corrosion processes. Sweet raw production facilities an Algerian field manifests inside surface installations, wh...

Objective(s): In this study, the neutralizing abilities of the equine and the recently introduced camelid antivenoms on the hemodynamic parameters (inotropism, chronotropism, and arrhythmogenicity) were assessed following envenomation by Hemiscorpius lepturus venom in rats. Materials and Methods: At first, the electrophoretic profiles of...