PURPOSE This study was designed to determine whether the ability to adversely affect corneal epithelial cell health is a factor common to Pseudomonas aeruginosa keratitis strains and to assess the prevalence of each pathogenic phenotype and genotype in a canine model of naturally-acquired P. aeruginosa ocular infection. METHODS P. aeruginosa ocular isolates were collected by sampling 100 dogs...

The incidence of complicated herpes simplex keratitis appears to have increased and the important factor seems to be associated with the use of topical corticosteroid hormone. A good experimental model exists for the study of herpetic keratitis. The disease corresponds to the primary infection in man. The unfavorable effects of corticosteroid hormone on experimental herpetic keratitis is reported.

Acanthamoeba keratitis is an uncommon but potentially devastating complication of contact lens wear. We present a case of Acanthamoeba keratitis in a soft-contact-lens wearer successfully treated with long-term medical therapy and penetrating keratoplasty. To our knowledge this is the first case of Acanthamoeba keratitis diagnosed in Canada.

BACKGROUND Corneal ulcer is an important cause of blindness in developing countries. Therapeutic keratoplasty for infective keratitis is a frequently performed surgery in these countries. OBJECTIVE To find out the outcome of therapeutic keratoplasty for infective keratitis. METHODS Records of 5 years were reviewed of patients who underwent therapeutic keratoplasty from 2006 to 2010. Data co...

PURPOSE To quantify the effect of topical corticosteroids on bacterial keratitis. CLINICAL RELEVANCE Bacterial keratitis is an economically important infection affecting 1 in 10,000 Americans annually. The predisposing factors, prior ocular health, infecting microorganisms, inflammatory severity, and therapeutic choices can affect the course and outcome. Antibacterial treatment is often curat...

PURPOSE To report the complication of infectious ulcerative keratitis after laser photocoagulation and pars plana vitrectomy (PPV) for retinopathy of prematurity (ROP). METHODS A retrospective chart review of infants treated for ROP with plus disease between 2004 and 2013 at University Hospital, Newark, New Jersey. RESULTS Of the 110 eyes (55 patients) that underwent treatment for ROP, 8 (7...

PURPOSE To report a keratoconic eye that developed severe sterile keratitis and corneal scar after collagen crosslinking necessitating corneal transplantation. CASE REPORT A 26-year-old man with progressive keratoconus underwent collagen crosslinking and presented with severe keratitis 72 hours after the procedure. The initial impression was infectious corneal ulcer and a fortified antibiotic...

ing improved outcomes. The result of longer healing times in fungal ulcers may be influenced by this. Re-epithelialization is a difficult endpoint tomeasure, particularly in fungal keratitis, so this result should be interpreted with some caution. Other factors associated with fungal and bacterial keratitis cases, such as geographic location of the patients, could act as confounders in this stu...

PURPOSE To report a case of Candida keratitis following penetrating keratoplasty in a patient with Candidiasis of the fingernails. CASE REPORT An 80 year-old male presented with recurrent Candida keratitis following penetrating keratoplasty. Patient was found to have evidence of Candidiasis of the fingernails. COMMENT Candidiasis of the fingernails have led to recurrent fungal keratitis fol...

objective: to assess the effect of heparin binding neurotrophic factor (hbnf) on sciatic nerve regeneration in animal model of rat. methods: seventy-five male wistar rats were divided into five experimental groups randomly (each group containing 15 animals): sham operation group (sham), autograft group (auto), transected control (tc), chitosan conduit (chit) and heparin binding neurotrophic fac...