OBJECTIVES To investigate whether neuromuscular performance predicts lower limb bone strength in different lower limb sites in postmenopausal women with mild knee osteoarthritis (OA). METHODS Neuromuscular performance of 139 volunteer women aged 50-68 with mild knee OA was measured using maximal counter movement jump test, isometric knee flexion and extension force and figure-of-eight-running...

Warming up before performing rigorous physical activity is typically done to increase range of motion and improve athletic performance. Common warm-up techniques in college athletics include static stretching, proprioceptive neuromuscular facilitation (PNF) stretching, dynamic warm-ups, and sport-specific activities. However, the type of warm-up routine used in the college setting varies based ...

The slow-channel congenital myasthenic syndrome (SCS) is an inherited neurodegenerative disease that caused mutations in the acetylcholine receptor (AChR) affecting neuromuscular transmission. Leaky AChRs lead to Ca(2+) overload and degeneration of the neuromuscular junction (NMJ) attributed to activation of cysteine proteases and apoptotic changes of synaptic nuclei. Here we use transgenic mou...

Purpose: The proper neuromuscular recruitment patterns of hip and knee muscles are essential for dynamic stabilization of the knee. According to the kinematic chain, weakness in the performance of one motor segment can affect other segments of motion. Thus, the aim of this study was to compare the isometric strength of selected muscles of lower extremities in the hyperpronated foot with t...

Neurotrophin-4 (NT-4) is produced by slow muscle fibers in an activity-dependent manner and promotes growth and remodeling of adult motorneuron innervation. However, both muscle fibers and motor neurons express NT-4 receptors, suggesting bidirectional NT-4 signaling at the neuromuscular junction. Mice lacking NT-4 displayed enlarged and fragmented neuromuscular junctions with disassembled posts...

How do infants, children, and adults learn grammatical rules from the mere observation of grammatically structured sequences? We present an embodied hypothesis that (a) people covertly imitate stimuli; (b) imitation tunes the particular neuromuscular systems used in the imitation, facilitating transitions between the states corresponding to the successive grammatical stimuli; and (c) the discri...

Declines in muscular strength resulting from reduced neural activity may influence the reduction in aerobic capacity in older men. However, there has been little investigation into the relationship between muscular strength and economy of movement during aerobic exercise in elderly subjects. Thus, the purpose of this study was to investigate the possible relationship between strength, aerobic p...

Objective: Neuromuscular injury prevention programs (IPP) can reduce injury rate by about 40% in youth sport. Multimodal IPP include, for instance, balance, strength, power, and agility exercises. Our systematic review and meta-analysis aimed to evaluate the effects of multimodal IPP on neuromuscular performance in youth sports. Methods: We conducted a systematic literature search including sel...

BACKGROUND Knee osteoarthritis (KOA) is a leading cause of public disability. Neuromuscular function contributes to the development and/or progression of KOA. Whole body vibration (WBV) exercise improve the neuromuscular function of patients with neurological disorders and even that of older patients with limited exercise options. Therefore, WBV exercise may offer an efficient and alternative t...