Objective: General anesthesia requires smooth endotracheal intubation, aided by neuromuscular blocking agents. Atracurium and cis-atracurium are non-depolarizing agents used for muscle relaxation. Succinylcholine, though effective, has undesirable side effects. This study aims to compare atracurium different doses of assess their onset, duration, recovery, hemodynamic effects, in order identify...

The effect of temperature on the potencies of neuromuscular blocking agents remains unclear. This study was undertaken to examine the effects of different neuromuscular blocking agents at 37 and 27 degrees C at a constant carbon dioxide content (alpha stat principle). The effect of neostigmine 1 mumol litre-1 induced antagonism of these agents was also investigated. Phrenic nerve-hemidiaphragm ...

background: we aimed to compare clinical effects of sugammadex versus combination of anticholinergic-anticholinesterase agents for reversing of nondepolarizing neuromuscular block in pediatric patients.materials and methods: a total of 60 pediatric patients  whom should be performed general anesthesia in the supine position were enrolled to this randomized double-blinded clinical trial.fentanyl...