نتایج جستجو برای: nerve sheath neoplasms

تعداد نتایج: 658028  

2017
Maurits de Vries Olaf van Tellingen Andel. G.L. van der Mey Antonius M.G. Bunt Inge Briaire-de Bruijn Pancras C.W. Hogendoorn

Background peripheral nerve sheath tumors comprise a broad spectrum of neoplasms. Vestibular schwannomas and plexiform neurofibromas are symptomatic albeit benign, but a subset of the latter pre-malignant lesions will transform to malignant peripheral nerve sheath tumors (MPNST). Surgery and radiotherapy are the primary strategies to treat these tumors. Intrinsic resistance to drug therapy char...

Background:   Valproic acid (VPA) is used to be an effective anti-epileptic drug and mood stabilizer. It has recently been demonstrated that VPA could promote neurite outgrowth, activate the extracellular signal regulated kinase pathway, and increases bcl-2 and growth cone-associated protein 43 levels in spinal cord. In the present research we demonstrate the effect of VPA on peripheral nerve r...

Journal: :The Journal of otolaryngology 2004
Farhan Ahsan Maggie K Lee Kim W Ah-See Andrea D Chapman

Malignant peripheral nerve sheath tumors of the nose and paranasal sinuses are extremely uncommon. We report the case of a 65-year-old woman who presented with a rapid emergence of "nasal polyps" that completely obstructed her nasal passages. Six years earlier she had been assessed elsewhere for nasal polyps. At presentation, the patient exhibited gross polyposis, with lesions protruding from b...

Journal: :AJNR. American journal of neuroradiology 2009
W S Fang L L Emerson J P Hunt K L Salzman

Soft tissue perineuriomas are an unusual type of peripheral nerve sheath tumors distinct from schwannomas and neurofibromas, with interesting histologic findings. They are not well characterized on radiographic examination. We report this case of a patient with sinonasal perineurioma to help define the imaging and pathologic features of this rare head and neck tumor.

Journal: :Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 2008
Katsuhiko Shimizu Riki Okita Yoko Uchida Jun Hihara

A 31-year-old man with neurofibromatosis 1 (NF1) was admitted for the treatment of solitary lung tumor. Nine months earlier he had undergone a large resection for malignant peripheral nerve sheath tumors (MPNSTs) in his back. Surgical resection of the right lower lobe was performed, and the tumor was pathologically diagnosed as a metastasis of MPNST. The survival of patients with pulmonary meta...

2006
Rosalie E Ferner

Neurofibromatosis 1 predisposes affected individuals to the development of benign and malignant tumours that are frequently disfiguring and difficult to manage. However, advances in molecular biology and the development of mouse models have facilitated our understanding of disease pathogenesis. Positron emission tomography has demonstrated that sophisticated imaging techniques have a role in di...

Journal: :AJNR. American journal of neuroradiology 2001
J H Lee H K Lee C G Choi D C Suh K S Lee S K Khang

SUMMARY We report the CT and MR findings in a patient with malignant peripheral nerve sheath tumor in the parapharyngeal space who had neither a family history nor stigmata of neurofibromatosis. A high-resolution CT scan of the temporal bone revealed bony erosion and widening of both the foramen ovale and the bony portion of the eustachian tube. A temporal bone MR image showed an intensely enha...

Journal: :Thorax 1960
B T LE ROUX

TERMINOLOGY Each axon cylinder is encased in a sheath of Schwann cells, and the tumour arising from this, the specific nerve sheath, is the Schwannoma or neurilemmoma. Groups of axon cylinders comprising a peripheral nerve are enmeshed in a non-specific sheath of fibrous tissue, and tumours arising from this non-specific nerve sheath are neurofibromata. In some nerve sheath tumours clear histol...

2014
Jordan D Frey Jo-Ann M Latkowski Eddie Louie Ernest S Chiu

1. Macarenco RS, Ellinger F, Oliveira AM. Perineurioma: a distinctive and underrecognized peripheral nerve sheath neoplasm. Arch Pathol Lab Med 2007;131:625-36. 2. Hornick JL, Fletcher CD. Intestinal perineuriomas: clinicopathologic definition of a new anatomic subset in a series of 10 cases. Am J Surg Pathol 2005;29:859-65. 3. Gupta K, Dey P, Vashisht R. Fine-needle aspiration cytology of mali...

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