نتایج جستجو برای: nerve recovery

تعداد نتایج: 356793  

2012
A.S. Pagnussat S.M. Michaelsen M. Achaval J. Ilha E.E.S. Hermel F.P. Back C.A. Netto

The most disabling aspect of human peripheral nerve injuries, the majority of which affect the upper limbs, is the loss of skilled hand movements. Activity-induced morphological and electrophysiological remodeling of the neuromuscular junction has been shown to influence nerve repair and functional recovery. In the current study, we determined the effects of two different treatments on the func...

Journal: :Leprosy review 1984
E M Touw-Langendijk J W Brandsma J G Andersen

A rigid corti co-steroid treatment regimen was given to borderline leprosy patients who had recent nerve function loss due to reversal reaction. In order to record nerve function changes objectively a nerve index was used which was based on the results of voluntary muscle testing and sensory testing. Ninetythreeulnar and median nerves were followed in this study. Improvement in ulnar nerve func...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Christelle Girard Song Liu Françoise Cadepond David Adams Catherine Lacroix Marc Verleye Jean-Marie Gillardin Etienne-Emile Baulieu Michael Schumacher Ghislaine Schweizer-Groyer

Peripheral nerves show spontaneous regenerative responses, but recovery after injury or peripheral neuropathies (toxic, diabetic, or chronic inflammatory demyelinating polyneuropathy syndromes) is slow and often incomplete, and at present no efficient treatment is available. Using well-defined peripheral nerve lesion paradigms, we assessed the therapeutic usefulness of etifoxine, recently ident...

Journal: :Proceedings of the Royal Society of Medicine 1936

Journal: :The Journal of clinical investigation 2011
Chi Him Eddie Ma Takao Omura Enrique J Cobos Alban Latrémolière Nader Ghasemlou Gary J Brenner Ed van Veen Lee Barrett Tomokazu Sawada Fuying Gao Giovanni Coppola Frank Gertler Michael Costigan Dan Geschwind Clifford J Woolf

Although peripheral nerves can regenerate after injury, proximal nerve injury in humans results in minimal restoration of motor function. One possible explanation for this is that injury-induced axonal growth is too slow. Heat shock protein 27 (Hsp27) is a regeneration-associated protein that accelerates axonal growth in vitro. Here, we have shown that it can also do this in mice after peripher...

Journal: :Neuroscience 2013
K L Lankford E J Arroyo C-N Liu C J Somps M A Zorbas D L Shelton M G Evans S I Hurst J D Kocsis

Elevated nerve growth factor (NGF) is believed to play a role in many types of pain. An NGF-blocking antibody (muMab 911) has been shown to reduce pain and hyperalgesia in pain models, suggesting a novel therapeutic approach for pain management. Since NGF also plays important roles in peripheral nervous system development and sensory nerve outgrowth, we asked whether anti-NGF antibodies would a...

Journal: :The Journal of bone and joint surgery. British volume 1965
C B FEARN J W GOODFELLOW

Unexplained paralysis of the muscles supplied by the anterior interosseous nerve of the forearm was recorded by Parsonage and Turner (1948), Kiloh and Nevin (1952) and Thomas (1962). In none of the patients they described was the affected nerve explored. Spontaneous recovery occurred in all, but it was long delayed and incomplete. We record here a case of “ isolated neuritis ofthe anterior inte...

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