BACKGROUND/AIMS Parstatin is a 41-mer peptide formed by proteolytic cleavage on activation of the protease-activated receptor 1. Parstatin was recently found to be cardioprotective against myocardial ischemia/reperfusion (IR) injury. In the present study, it was hypothesized that parstatin would protect the kidneys in acute renal failure. METHODS We investigated the effects of parstatin on th...

Aim: The aim of the present investigation is to study nephroprotective activity two indigenous medicinal plants. Material and methods: Dried leaves Alstonia scholaris Centella asiatica were procured from garden campus Pharmacy College in month September, Bhopal, Madhya Pradesh, India. Around 500 gm dried coarsely powdered weighed filled Soxhlet apparatus for extraction. Wistar albino rats eithe...