Background Cancer of the cervix is a common cause malignancy. Its association with systemic lupus erythematosus (SLE) debatable. Objective Early detection cervical pre-neoplastic lesion in SLE patients. Method A case control study was performed on 64 group and using colposcopy, pap smear histopathological examination. Conclusion This revealed that preneoplastic neoplastic lesions were higher gr...

was induced by carcinogen treatment. Many cell types in culture undergo a process of neoplastic transformation spon taneously, i.e., in the absence of a known carcinogenic insult (31). During this transformation process, aneuploid cell lines arise that are often nontumorigenic in animals when injected as a cell suspension. These lines are generally termed “nor mal' â€ãnd are frequently used a...

New research data for low-dose, low-linear energy transfer (LET) radiation-induced, stochastic effects (mutations and neoplastic transformations) are modeled using the recently published NEOTRANS(3) model. The model incorporates a protective, stochastic threshold (StoThresh) at low doses for activating cooperative protective processes considered to include presumptive p53-dependent, high-fideli...

In surgical neuropathology, as in other areas of pathology, before making a diagnosis of “tumor” the possibility of a non-neoplastic process should be fully considered and excluded. “Gliosis” is a non-specific change that is encountered quite often in routine practice and may accompany both neoplastic and nonneoplastic conditions. Because there is usually some type of pathological process that ...

Dysgranulopoiesis is a condition in which granulocytic production defective and most often described neoplastic conditions. However, it can also be frequently seen non-neoplastic Early suspicion detection of these causes may prevent further invasive expensive interventions. In this review, we take look at the various dysgranulopoiesis with an emphasis on etiologies, followed by detailed outline...

Carcinogenesis is a multistep process involving alterations in at least two distinct classes of genes. Protooncogenes are activated qualitatively or quantitatively in certain tumors, and they appear to act as positive proliferative signals for neoplastic growth. In contrast, tumor suppressor genes are normal genes that must be inactivated or lost for tumor development. When active, tumor suppre...

Background: Appendiceal cancer as a cause of appendicitis is a rare event occurring in approximately 1.0% of all cases of appendicitis. Nevertheless, treatment of appendiceal cancer as appendicitis may have an adverse outcome for the patient, even iatrogenically converting a contained malignant process into a disseminated disease that will have a lethal outcome. Methods: Staging of appendiceal ...

cells in the leptomeninges and subarachnoid space. Its incidence seems to be rising because of improvements in the systemic treatment of malignant neoplasms of the hematopoietic system and of other types of cancer. To provide an objective basis for therapeutic decision-making, the authors performed a Medline search of all articles published from January 1975 to December 2005 with the following ...