conclusions the fev1/fev6 ratio can be used as a valid surrogate for fev1/fvc in the diagnosis of airway obstruction, especially for screening purposes in high-risk populations for copd. moreover, fev6 is an acceptable alternative for fvc in detection of restrictive pattern. results this study shows that the current cut-off points used to detect obstruction and restriction can be replaced by fe...

ubiquicidin (ubi) [29-41] is a synthetic cationic antimicrobial peptide that preferentially binds to bacterial cell membrane at the site of infection. we aimed to assess diagnostic value of 99mtc-ubi [29-41] as a radiopharmaceutical in differentiation of bacterial infection from sterile inflammation in suspected orthopedic implants. nine patients suspected for orthopedic implant infection, all ...

ABBREVIATIONS HR: high risk NPV: negative predictive value TcB: transcutaneous bilirubin TSB: total serum bilirubin www.hospitalpediatrics.org doi:10.1542/hpeds.2012-0012 Address correspondence to Gary A. Emmett, MD, Department of Pediatrics, 833 Chestnut St, Suite 300, Philadelphia, PA 19107. E-mail: [email protected] HOSPITAL PEDIATRICS (ISSN Numbers: Print, 2154 1663; Online, 2154 1671). C...

BACKGROUND Complete excision is important for proper surgical treatment of thyroid disorders. Functional thyroid tissue can be identified based on the level of serum thyroglobulin (Tg), which is produced only by the thyroid follicular cells, and nuclear scan. METHODS Serum thyroid stimulating hormone (TSH), free thyroxin (FT4), basal (unstimulated) Tg and anti-Tg antibody (anti-Tg ab) were me...

INTRODUCTION The objectives were to assess the diagnostic value of hysterosalpingography (HSG) with laparoscopy as gold standard in the evaluation of tubal patency and pelvic adhesions in women suffering from infertility. METHODS We conducted a comparative cross sectional study on 208 medical files of infertile women followed up at the Yaoundé General Hospital during a period of five years (D...

objectives: presence/absence of cervical lymph node metastasis plays a critical role in prognosis and survival of patients with oral squamous cell carcinoma (scc). this study was designed to assess the diagnostic accuracy of computed tomography (ct) scan for detection of cervical lymph node metastasis in oral scc in comparison with histopathological analysis after neck dissection methods: in th...

INTRODUCTION We evaluated the UroVysion (Abbott Molecular, IL, USA) fluorescence in situ hybridization (FISH) assay for the diagnosis of urothelial cancer in patients diagnosed with or suspected to have bladder, upper tract urothelial carcinoma (UTUC), and combined upper and lower tract urothelial carcinoma (BC). MATERIALS AND METHODS A single institution retrospective analysis comparing sens...

Background MNSI is widely used for evaluation of distal symmetric peripheral polyneuropathy (PPN) in individuals with diabetes. In the DCCT/EDIC study, the MNSI was validated for screening of signs and symptoms of PPN, presenting, for a cutoff of ≥2.5, sensitivity of 61%, specificity of 79%, positive predictive value (PPV) of 55% and negative (NPV) of 83%, when compared to neurological examinat...

Mesothelin has been proposed as a useful tool in the diagnosis of malignant pleural mesothelioma (MPM). We aimed to examine its diagnostic utility and the impact of renal impairment on results. We prospectively recruited 230 patients with new undiagnosed pleural effusions, testing serum (n=216) and pleural fluid (n=206) mesothelin (by ELISA) during the initial consultation. 28 (12%) out of 230 ...

BACKGROUND AND OBJECTIVES Many cases of gastrointestinal (GI) tumors as lymphoma, adenocarcinoma, and most of submucosal tumors (SMT) such as gastrointestinal stromal tumor (GIST) and leiomyoma are difficult to diagnose as they frequently yield negative endoscopic biopsies. We evaluated the accuracy of endoscopic ultrasound (EUS) and EUS-guided fine-needle aspiration (EUS-FNA) in the diagnosis ...