OBJECTIVE The purpose of this study was to elucidate the role of microRNA-130a (miR-130a) in obstructive sleep apnea hypopnea syndrome (OSAHS)-associated pulmonary hypertension (PHT) by targeting the growth arrest-specific homeobox (GAX) gene. METHODS A total of 108 patients with OSAHS-associated PHT were recruited as the OSAHS-associated PHT group and 110 healthy individuals were randomly se...

An experiment was conducted to evaluate the effect of diets with reduced energy level content, supplemented carbohydrase, on broiler performance and coefficient metabolizability nutrients. A total 720 one-day-old male Cobb-500 chicks were distributed in a completely randomized design, six treatments, eight repetitions 15 birds each. The treatments were: (1) positive control, basal diet meet req...

BACKGROUND The use of a toothbrush has a limited ability to control the dental biofilm in interproximal areas. Therefore, specialized devices, such as dental floss, may be useful for these specific areas. OBJECTIVE This study aimed to investigate the efficacy of dental floss impregnated with 5% chlorhexidine gluconate on the reduction of the supragingival biofilm. METHODS This research was ...

A complex set of extracellular signals is required for neural crest (NC) specification. However, how these signals function to coordinate cell cycle progression and differentiation remains poorly understood. Here,we report inXenopus a role forStat3 inthis process downstream of FGF signaling. Depletion of Stat3 inhibited NC gene expression and proliferation while its overexpression expanded the ...

Nicotine caused significant increase in the serum Cholesterol, Triglyceride, VLDL, LDL & significant reduction in HDL level. Premna integrifolia & Atorvastatin treatment showed significant prevention in increased serum Cholesterol, Triglyceride, LDL as compared to Nicotine control (NC) group. While HDL level was significantly increased in treated & standard group as compared to Nicotine control...

The present study aimed to investigate the role and underlying mechanisms of microRNA16 (miR-16) on proliferation, apoptosis and invasion of glioma cells. The cell models of miR-16 upregulation and Negative control group (NC group) were built. The cell functions of different groups were detected by colony formation assay, transwell chamber assay, proliferation, apoptosis and cycle experiments. ...

Using dietary fibre to control childhood diarrhoea has rarely been discussed. However, dietary fibre is being proposed to prevent diarrhoea in piglets. The present study aimed to study the effects of introducing fibre in the post-weaning piglet diet and its particle size on the intestinal ecosystem before and after an experimental infection with Escherichia coli. A total of thirty-six post-wean...

The present study aimed to investigate the role of transcription factor E3 (TFE3) in the regulation of proliferation in renal adenocarcinoma cells. The LV‑TFE3 overexpression (OE) lentivirus and negative control CON195 (NC) lentivirus were transfected into the ACHN cell line. Protein expression of FLAG‑tag TFE3 was determined using western blot analysis. Differences in cell proliferation, plate...