the antimicrobial activity of thirty six novel dihydropyrimidine derivatives was evaluated against common pathogenic bacteria. significant antimicrobial activity (mic=32, 64 µg/ml) was observed. escherichia coli and pseudomonas aeruginosa as gram-negative bacteria and staphylococcus aureus as gram-positive bacteria were determined to be the most susceptible pathogens in this study. the highest ...

Bacterial sepsis is a major cause of fatality worldwide. Sepsis is a multi-step process that involves an uncontrolled inflammatory response by the host cells that may result in multi organ failure and death. Both gram-negative and gram-positive bacteria play a major role in causing sepsis. These bacteria produce a range of virulence factors that enable them to escape the immune defenses and dis...

background/objective: neonatal septicemia is one of the major causes of mortality in newborns. the aim of this study is to evaluate the clinical manifestations and laboratory findings in positive blood culture in neonatal septicemia. methods: in this retrospective study, we allocated 100 records positive blood culture of neonates suffering from septicemia. a questionnaire was completed for each...