Paclitaxel (PTX) is a effectively chemotherapeutic agent which is extensively able to treat the non-small cell lung, pancreatic, breast and other cancers. But it is a practically insoluble drug with water solubility less than 1 µg/mL, which restricts its therapeutic application. To overcome the problem, hyaluronic acid-complexed paclitaxel nanoemulsions (HPNs) were prepared by ionic complexatio...

With time, dosage forms have progressed, from essential tablets to advanced systems, which are now more focused on providing better ease of administration the patients. One such advantageous novel drug delivery system is Nanoemulsion based delivery. The Nanoemulsion-based reasonably a new means enhancing delivery; Nanoemulsions sub-micron size particles roughly in range 50-600 nm. review focuse...

Acinetobacter baumannii has emerged as a serious problematic pathogen due to the ever-increasing presence of antibiotic resistance, demonstrating a need for novel, broad-spectrum antimicrobial therapeutic options. Antimicrobial nanoemulsions are emulsified mixtures of detergent, oil, and water (droplet size, 100 to 800 nm) which have broad antimicrobial activity against bacteria, enveloped viru...

The purpose of this study was to prepare Brucea javanica oil cationic nanoemulsions (BJO-CN) with BJO as drug as well as oil phase and chitosan as cationic inducer, to explore the practical suitability of using cationic nanoemulsions for oral delivery of mixed oil, and to test its bioavailability and antitumor effect. BJO-CN was prepared by chitosan solution stirring method and then characteriz...

BACKGROUND Preparation of nanoformulations using natural products as bioactive substances is considered very promising for innovative larvicidal agents. On this context, oil in water nanoemulsions develop a main role, since they satisfactorily disperse poor-water soluble substances, such as herbal oils, in aqueous media. Pterodon emarginatus, popularly known as sucupira, has a promising bioacti...

This research studies the application of a specific nanoemulsion as anti-Escherichia coli agent. The mixture was generated by simplex-centroid design. Physicochemical parameters such droplet average diameter, pH, viscosity, density, turbidity, whitening index, refractive stability (thermal, physical, and osmotic stability), antibacterial activity kinetic, have been assessed. nanoemulsions had d...

Inflammation is considered a natural reaction of the immune system that can be caused by several factors such as pathogens, chemical substances, and damaged cells. Since classical era, therapeutic substances have been made from medicinal plants. According to recent studies, nanotechnology provides fresh approach maintaining standard quality, distribution, bioactivity compounds. This review emph...