In this work, we introduce the history and mechanisms of surface enhanced Raman scattering (SERS), discuss various techniques for fabrication of state-of-the-art SERS substrates, and review recent work on robotizing plasmonic nanoparticles, especially, the efforts we made on fabrication, characterization, and robotization of Raman nanosensors by design. Our nanosensors, consisting of tri-layer ...

A simple stability-indicating RP-HPLC/UV method was validated for determination of beclomethasone dipropionate (BD) in nanocapsule suspensions. Chromatographic conditions consisted of a RP C18column (250 mm x 4.60 mm, 5 μm, 110 Å), using methanol and water (85:15 v/v) as mobile phase at 1.0 mL/ min with UV detection at 254 nm. The calibration curve was found to be linear in the concentration ra...

This paper describes characterization of lyophilized lipid nanocapsules loaded with Alexa 488 by fluorescence correlation spectroscopy (FCS). Fluorimetry analysis of nanocapsules containing self-quenching concentrations of 5- and 6-carboxyfluorescein was performed to establish a point of reference for FCS. FCS results complemented the results obtained by fluorimetry for a bulk nanocapsule solut...

Infections arising from contaminated medical devices are a serious global issue, contributing to antibiotic resistance and imposing significant strain on healthcare systems. Since the majority of medical deviceassociated infections are biofilm related, efforts are being made to generate either bacteria-repellent or antibacterial coatings aimed at preventing bacterial colonisation. Here, we util...

A solution phase-based nanocapsule method was successfully developed to synthesize non-platinum metal catalyst-carbon supported Ag nanoparticles (Ag/C). XRD patterns and TEM image show Ag nanoparticles with a small average size (5.4 nm) and narrow size distribution (2-9 nm) are uniformly dispersed on the carbon black Vulcan XC-72 support. The intrinsic activity and pathway of oxygen reduction r...

The objective of this work was to characterize the cinnamon oil nanocapsule that contained alginate-chitosan as coating agents. In this work, cinamonn oil loaded chitosan nanoparticles (CS-alginate NP-cinamonn) are prepared by a two-step process including oil/water emulsion and ionic gelation. In this study, cinamon as a core material was nanoencapsulated with chitosan alginate at a ratio of 1:...

In this study, n-dodecanol and 1-tetradecanol were nanoencapsulated by poly(methyl metharcylate-co-methacrylic acid) (p(MM-co-MA)) wall using emulsion polymerization method which was defined as one-stage (OS) or two-stage (TS). Nanocapsules analyzed Fourier-transform infrared (FT-IR) spectroscopy, transmission electron microscopy (TEM), differential scanning calorimeter (DSC) thermogravimetric ...

Peroxidase-like nanozymes are nanoscale materials that can closely mimic the activity of natural peroxidase for a range oxidation reactions. Surface coating with polymer nanogels has been considered to prevent aggregation nanozymes. For long time, understanding largely limited its stabilization effect on nanozyme in aqueous media, while little is known about how plays role interaction substrate...