نتایج جستجو برای: naja naja oxiana
تعداد نتایج: 693 فیلتر نتایج به سال:
Reaction of phospholipase A, (Naja naja naja) with pbromophenacyl bromide leads to almost complete loss of enzymatic activity. The rate of inactivation is pa-dependent with ,pK, = 6.9 for the ionizing residue. p-Bromophenacyl bromide modifies 0.5 mol of histidinelmol of enzyme as judged by amino acid analysis and incorporation studies with W-labeled reagent. The rate of inactivation is affected...
Phospholipases A2 from pig pancreas and the venoms from bee, Naja naja and Crotalus atrox have been studied by using a new continuous fluorescence displacement assay that utilizes normal phospholipid substrates [Wilton (1990) Biochem. J. 266, 435-439]. With limiting amounts of substrate, the assay demonstrated stoichiometric conversion into products with both pancreatic and venom enzymes, and t...
Over 24 years, from 1976 to 1999, we conducted a prospective study of overall and cause-specific mortality among the population of 42 villages of south-eastern Senegal. Of 4228 deaths registered during this period, 26 were caused by snakebite, 4 by invertebrate stings and 8 by other wild or domestic animals. The average annual mortality rate from snakebite was 14 deaths per 100,000 population. ...
Objective(s): Malaria is an important parasitic disease with high morbidity and mortality in tropical areas. Resistance to most antimalarial drugs has encouraged the development of new drugs including natural products. Venom is a complex mixture of active pharmaceutical ingredients. The purpose of this study was to investigate the antimalarial activity of purified frac...
The crystal structure of a complex between a phosphonate transition-state analogue and the phospholipase A2 (PLA2) from Naja naja atra venom has been solved and refined to a resolution of 2.0 angstroms. The identical stereochemistry of the two complexes that comprise the crystal's asymmetric unit indicates both the manner in which the transition state is stabilized and how the hydrophobic fatty...
Objectives: The present study focuses on development of novel Metal-Herbal Nano composite (MHNC) formulation against Naja naja and Bungarus Caeruleus venoms animal models. Methods: were procured from Irula snake catchers society in lyophilised forms. Herbal-metal nanocomposites prepared 1:1 combinations. Single strength concentration Leucas zeylanica extracts copper oxide metal nanoparticles wa...
The effects of the venoms of Naja melanoleuca, Naja nigricollis, and Ophiophagus hannah on blood coagulation, platelet aggregation, and fibrinolysis were studied in vitro. All three venoms were shown to be anticoagulant. This action appeared to be due to an effect on both the extrinsic and blood thromboplastin mechanisms. Platelet aggregation in Chandler's tubes and adenosine diphosphate reacti...
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