Knowledge of the anatomy and function of the nail apparatus is essential when performing the physical examination. Inspection may reveal localized nail abnormalities that should be treated, or may provide clues to an underlying systemic disease that requires further workup. Excessive keratinaceous material under the nail bed in a distal and lateral distribution should prompt an evaluation for o...

SLE: systemic lupus erythematosus INTRODUCTION Pincer nail is the transverse overcurvature of the nail plate which can lead to painful pinching of underlying tissues, loss of soft tissue of the involved fingers, and rarely bone resorption of the terminal phalynx. Pincer nails may be congenital or acquired. Acquired pincer nail deformity has multiple associations including ill-fitting shoes, med...

BACKGROUND Vitiligo is an acquired pigmentary skin disorder affecting 0.1-4% of the general population. The nails may be affected in patients with an autoimmune disease such as psoriasis, and in those with alopecia areata. It has been suggested that nail abnormalities should be apparent in vitiligo patients. OBJECTIVE We sought to document the frequency and clinical presentation of nail abnor...

INTRODUCTION Psoriasis affects about 1-2% of the entire population. Due to its chronicity and relapsing course, psoriasis has a great influence on patients' quality of life and psychological status. AIM To evaluate apprehensaion of the disease by psoriatic patients. MATERIAL AND METHODS One hundred psoriasis patients (36 females, 64 males; mean age 47.3 ±15.8 years) were enrolled. Mean psor...

Psoriatic onychodystrophy affects up to 50% of patients with psoriasis and 80% psoriatic arthritis, an estimated lifetime risk nail plate changes in this patient population 90%. Nail is characterised by a variety morphological resulting from the inflammation matrix or bed, leading functional impairment negative impact on patient’s quality life. distinct therapeutic problem, as its localization ...

To identify patients that benefit most from ixekizumab (IXE), unsupervised machine learning applied to Psoriasis Area and Severity Index (PASI) improvement was used define IXE-response clusters in with psoriasis. Using these identified based on PASI, responses challenging body areas (CBA) as well Static Physicians Global Assessment (sPGA) were assessed through 52 weeks. These analyses included ...

A common skin disorder called psoriasis causes thickened patches of the skin. Typically, it is discovered to be covered with silvery scales. Although regarded as a condition, actually outcome an immune system dysfunction. Types psoriasis-Plaque (psoriasis vulgaris), Pustular psoriasis, Nail Guttate Flexural Erythrodermic psoriasis. Activated T cells go into from circulation and lymph nodes rele...