Biochemicals 5-hydroxytrptophan, 5-hydroxy indole acetic acid, ketanserin, bicuculline, baclofen, atropine, sodium octyl sulfonic acid, ethylene diamine tetra acetic acidEDTA, D-glucose, calcium chloride, bovine serum albumin fraction V, Superoxide dismutase from bovine erythrocytes were purchased from Sigma Chemical Co., St. Louis, USA. All other reagents were of analytical grade purchased loc...

The preparation of 5-bromo-2-naphthol (4) in three steps from 5-amino-2-naphthol (1) is described. A sulfonic acid group is introduced at the 1-position as an activating and protecting group for the Sandmeyer reaction. The sulfonate group allows for the use of only water and sulfuric acid as solvents. The sulfonic acid is introduced with three equivalents of sulfuric acid, and it is removed in ...

In this study, a quinoline-4-carboxylic acid derivative was synthesized through Pfitzinger reaction. reaction, isatin is modified via its reaction with ketone and refluxed for 24 h to obtain acid. The presence of carboxylic group identified by Fourier Transform Infrared (FTIR) spectroscopy ultraviolet–visible (UV-Vis) spectrophotometry. results showed that the absorption peaks C=O O–H stretchin...

approved: T. Mark Zabriskie L-pipecolic acid (L-PA), a six carbon imino acid, is an intermediate of lysine degradation in various organisms including bacteria, yeast, fungi and mammals. In primates, the oxidation of L-PA by the enzyme L-pipecolate oxidase (L-PO) is the rate determining step of L-lysine degradation in the central nervous system. This thesis describes efforts to probe the L-PO me...

Mycoplasma pneumoniae harvested from media which had become acid lost the ability both to induce formation of tetrazolium reduction inhibition antibody and to act as antigens in immunodiffusion against human convalescent-phase sera. Incorporation of N-tris(hydroxymethyl)-2-aminoethane sulfonic acid and N-2-hydroxyethylpiperazine-N'-2-ethane sulfonic acid buffers into a new medium containing PPL...

Core–shell zirconia-coated magnetite nanoparticle bearing sulfonic acid groups (nano-Fe3O4@ZrO2-H3PO4) have been prepared and used as an efficient acid catalyst in the synthesis of fluoroquinolons by the direct amination of 7-halo-6- fluoroquinolone-3-carboxylic acids with variety of piperazine derivatives and (4aR,7aR)-octahydro-1H-pyrrolo...

Core–shell zirconia-coated magnetite nanoparticle bearing sulfonic acid groups (nano-Fe3O4@ZrO2-H3PO4) have been prepared and used as an efficient acid catalyst in the synthesis of fluoroquinolons by the direct amination of 7-halo-6- fluoroquinolone-3-carboxylic acids with variety of piperazine derivatives and (4aR,7aR)-octahydro-1H-pyrrolo...