AIMS Understanding the molecular mechanisms of underlying disease has led to a movement away from the one-drug-fits-all paradigm towards treatment tailored to the genetic profile of the patient. The Biocartis Idylla platform is a novel fully automated, real-time PCR-based in vitro diagnostic system. The Idylla NRAS-BRAF mutation test has been developed for the qualitative detection of mutations...

glycoconjugates and their programmed changes during the course of development in the cell-surface as well as in the extracellular matrix, are known to affect cell differentiation, cellular interaction and other developmental phenomena during embryogenesis. the purpose of this study was to localize n-acetylgalactosamin as well as fucose-containing glycoconjugates in situ during thymus developmen...

The results obtained from a study of the thermal transformations polymorphic long-chain normal paraffins (n-C32H66 and n-C36H74) are presented here. research was performed using power-compensated Differential Scanning Calorimeter (DSC). Both heating cooling experiments were in dynamic nitrogen atmosphere. Thermodynamic data for both transitions, as well fusion endotherms, determined DSC curves....

Materials and Methods Formalin-fixed paraffin-embedded lung SqCC (n=137) and LADC (n=60) tissue microarrays were acquired. DSG3/p40 + Napsin A double stain cocktail (Biocare Medical, Concord, CA), TTF-1 [SPT24] and TTF-1 [8G7G3/1] antibody titers were optimized for IHC. SPT24 was optimally titered at 1:1200. The double stain antibody cocktail was detected by using a polymer double stain detecti...

The article deals with the process of “waxing” pipes and choice effective measures to prevent these negative phenomena. To assess nature asphalt-resin-paraffin deposits (ARPD) select a further investigation scheme, X-ray Spectral analysis was used. It is shown, that ARPD complex system structured by resinous-asphaltene substances paraffin-naphthenic or paraffin-aromatic hydrocarbons.Mass transf...

The low thermal conductivity of phase change material (PCM) leads to low heat storage/retrieval rates. The expanded graphite (EG) was used to enhance the thermal conductivity. EG/paraffin composite with the 7% mass fraction of EG was prepared as a good candidate for the latent thermal energy storage (LTES) system. A shell and tube LTES system built for room heating and hot water supply in a fam...

Photoinduced twisted intramolecular charge transfer (TICT) of meso-(4-dimethylamino)phenylamino subporphyrin and meso-(4-nitro)phenylamino subporphyrin has been revealed by steady-state and time-resolved absorption/fluorescence experiments and quantum calculations. Subporphyrins and undergo molecular twisting at the Cmeso-N bond and the N-Cipso bond, respectively, to trigger intramolecular char...

OBJECTIVE Follicular lymphoma (FL) is one of the most common lymphomas, and is characterized by t(14;18)(q32;q21) in more than 80% of patients. The aim of this study was to determine the rate of t(14;18) positivity based onthe detection of mbr or mcr in paraffin-embedded tissue samples. MATERIAL AND METHODS The study included 32 paraffin-embedded tissue samples collected from 32 consecutive F...

The double alkylation of N-vinylpyrrolidone (N-VP) with 1,8-dibromooctane yields paraffin-like oligomeric chains bearing polymerizable vinyl moieties. These oligomers were radically crosslinked in bulk with N-VP as co-monomer yielding swellable polymer disks. The vinylic side groups of the N-VP oligomers allow thiol-ene click reactions with 2-aminoethanethiol hydrochloride to obtain reactive am...