نتایج جستجو برای: n 43
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TDP-43 is an RNA-binding protein active in splicing that concentrates into membraneless ribonucleoprotein granules and forms aggregates in amyotrophic lateral sclerosis (ALS) and Alzheimer's disease. Although best known for its predominantly disordered C-terminal domain which mediates ALS inclusions, TDP-43 has a globular N-terminal domain (NTD). Here, we show that TDP-43 NTD assembles into hea...
the molecule(s) recognized by all four of the antibodies are consumed in the clotting process and that this molecule(s) is fibrin(ogen). AHF2: 1 reacted with fibrinogen separated in SDS/polyacrylamide-gel electrophoresis under reducing conditions followed by Western blotting on to nitrocellulose to reveal two bands of molecular mass 60.5 kDa and 64.4 kDa. These bands correspond to the A-a bands...
Connexin 43 (Cx43alpha1) gap junction has been shown to have an essential role in mediating functional coupling of neural crest cells and in modulating neural crest cell migration. Here, we showed that N-cadherin and wnt1 are required for efficient dye coupling but not for the expression of Cx43alpha1 gap junctions in neural crest cells. Cell motility was found to be altered in the N-cadherin-d...
The cuticular lipid compounds, usually named waxes, present in the layering of Quercus suber adult leaves were extracted with solvents different polarities (n-hexane, dichloromethane and acetone) analysed by GC–MS. Q. have a substantial wax layer (2.8% leaf mass 239 μg/cm2), composed predominantly terpenes (43–63% all compounds), followed aliphatic long chain molecules, mainly fatty acids, smal...
Reduced expressions of plakoglobin and connexin 43 have been reported in the myocardium of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). However, the relationships between these expression abnormalities and the clinical features of ARVC remain unknown.The expressions of plakoglobin and connexin 43 in myocardial biopsy specimens from 10 patients with confirmed ARVC, and 1...
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