Forslund, Anders H., Antoine E. El-Khoury, Roger M. Olsson, Anders M. Sjödin, Leif Hambraeus, and Vernon R. Young. Effect of protein intake and physical activity on 24-h pattern and rate of macronutrient utilization. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E964–E976, 1999.— Effects of moderate physical activity (90 min at 45–50% of maximal O2 uptake 2 times daily) and ‘‘high’’ (2.5 g prote...

Taylor, Mark S., Hong Gao, Jason D. Gardner, and Joseph N. Benoit. Effects of IBMX on norepinephrineinduced vasoconstriction in small mesenteric arteries. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G909–G914, 1999.—The present study assesses the effects of the phosphodiesterase inhibitor IBMX on norepinephrine (NE)-induced constriction of small mesenteric arteries. Arteries (,150 μm...

Stallknecht, Bente, Joop Madsen, Henrik Galbo, and Jens Bülow. Evaluation of the microdialysis technique in the dog fat pad. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E588–E595, 1999.—In the present study the microdialysis technique was evaluated in an isolated autoperfused dog fat pad. Concentrations of glucose, lactate, and glycerol were measured in interstitial fluid by microdialysis and ...

Muscará, Marcelo N., and John L. Wallace. Nitric Oxide. V. Therapeutic potential of nitric oxide donors and inhibitors. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G1313–G1316, 1999.—Nitric oxide is a crucial mediator of gastrointestinal mucosal defense, but, paradoxically, it also contributes to mucosal injury in several situations. Inhibitors of nitric oxide synthesis and compounds...

Coopersmith, Craig M., David O’Donnell, and Jeffrey I. Gordon. Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G677–G686, 1999.—Little is known about the effects of ischemia-reperfusion on the inductive, commitment, or execution phases of apoptosis. We have created a genetically defined...

HANS BARLE,1 PIA ESSÉN,1 BJÖRN NYBERG,2 HANS OLIVECRONA,2 MICHAEL TALLY,3 MARGARET A. MCNURLAN,4 JAN WERNERMAN,1 AND PETER J. GARLICK4 1Department of Anesthesiology and Intensive Care and 2Department of Surgery, Huddinge University Hospital, S-141 86 Huddinge; 3Department of Endocrinology, Karolinska Hospital, S-104 01 Stockholm, Sweden; and 4Department of Surgery, University Medical Center, St...

Gupta, Sanjeev, Pankaj Rajvanshi, Emma Aragona, Chang-Don Lee, Purnachandra R. Yerneni, and Robert D. Burk. Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G629– G638, 1999.—To understand regulation of transplanted hepatocyte proliferation in the normal liver, we used genetically ...

The global food system makes a significant contribution to climate changing greenhouse gas emissions with all stages in the supply chain, from agricultural production through processing, distribution, retailing, home food preparation and waste, playing a part. It also gives rise to other major environmental impacts, including biodiversity loss and water extraction and pollution. Policy makers a...

Ghigo, E., G. Aimaretti, M. Maccario, G. Fanciulli, E. Arvat, F. Minuto, G. Giordano, G. Delitala, and F. Camanni. Dose-response study of GH effects on circulating IGF-I and IGFBP-3 levels in healthy young men and women. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E1009–E1013, 1999.—The aim of our study was to define the dose-response effect of a short-term treatment with different recombinant...

Cirrus clouds above Zurich's local mountain Uetliberg (871m). Cirrus clouds exist in the upper troposphere, at altitudes between 7 and 17 km. Because cirrus clouds cover up to 30% of the Earth surface they play an important role in atmospheric chemistry and climate (photo: SPARC Office; feel free to provide photos for future SPARC newsletters).