In continuance of search for new compounds we report herein the expedient and optimized synthesis a series N-(4-substituted phenyl)-7-hydroxy-4-methyl-2-oxoquinoline-1(2H)-carbothioamides (5a-g) in good yields. The anticancer antioxidant activities were determined as per standard protocol. Nearly 5 dozens cancer cell lines derived from nine different panels are used study activity was calculate...

This study used density functional theory and the quantum transport method to investigate interfacial coupling spin of transition metals (TMs) with a Fe, Co, Ni/2H-VSe2 hybrid nanostructure. Because indirect TM-Se-V led an obvious reduction magnetic moment disappearance half-metal characteristics 2H-VSe2, expected spin-filtering effect individual TMs 2H-VSe2 deteriorated at contact region. Neve...

The title compound 6-amino-3-benzylmercapto-1,2,4-triazolo[3,4-f][1,2,4]-triazin-8(7H)-one (4), molecular formula C(11)H(10)N(6)OS, was obtained by the reaction of 3-amino-2-benzyl-6-hydrazino-1,2,4-triazin-5(2H)-one (3) with carbon disulfide in a water/pyridine mixture. Compound 4 can also be synthesized by reacting 6-amino-3(2H)mercapto-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(7H)-one (7) with b...

3-Amino-l,2-benzisothiazole-1,1-dioxides (2b-n) have been prepared by heating saccharin (1) and the hydrochlorides of primary and secondary aliphatic amines with phosphorus pentoxide and N,N-dimethylcyclohexylamine at 240 °C. 3-Aminothieno[3,4-d]isothiazole-1,1-dioxides (6a-c) were similarly prepared from thieno[3,4-d]isothiazol3(2H)-one-1,1 -dioxide (5). 3 1 P NMR spectra were obtained of reac...

OBJECTIVE The purpose of this study was to compare an in vivo test of whole-body glycolysis, the deuterated-glucose disposal test (2H-GDT), with insulin sensitivity measured by the euglycemic-hyperinsulinemic glucose clamp and the steady-state plasma glucose (SSPG) test. RESEARCH DESIGN AND METHODS The 2H-GDT consists of an oral glucose challenge containing deuterated glucose, followed by mea...

It is proven that a graph with n vertices and minimum degree at least h+2 2h n contains n h ? O(h 2) vertex disjoint cycles of size h, and that a graph with n > N(h) vertices and minimum degree at least h+3 2h n contains n h vertex disjoint h-cycles, provided h divides n. Bounds on the minimum degree required for G to contain a factor consisting of cycles of speciied lengths are also discussed....

In the title mol-ecule, C(10)H(13)N(3)O(3)S·2H(2)O, the thio-semi-carbazide =N-NH-C(=S)-NH- fragment [torsion angle = 0.2 (1)°] is nearly coplanar with the benzene ring [dihedral angle = 2.4 (1)°]. The benzene ring and semicarbazide moiety are located on opposite sites of the C=N bond, showing an E configuration. The hy-droxy, imino and water H atoms are engaged in extensive hydrogen bonding, f...

A novel 3-D cuprous iodide polymer [CuI(μ6-L)]n with a Cu/I ratio as high as 3 (1, H2L = 1,3-bis(2H-tetrazol-5-yl)benzene) has been hydrothermally synthesized. The 3-D framework of 1 is constructed by the linkages of rare 1-D cationic aggregates [CuI2+]n and anionic bi-tetrazolate bridges. 1 shows unusually thermochromic luminescent and photocatalytic properties, and its density functional theo...