AIMS To evaluate the inter-study reproducibility of quantitative cardiovascular magnetic resonance (CMR) myocardial perfusion imaging and the influence of diurnal variation on perfusion. Data on these are limited, despite being crucially important for performing serial examinations both in clinical practice and in trials. METHODS AND RESULTS Sixteen healthy volunteers underwent high-resolutio...

INTRODUCTION Myocardial arterial spin labeling (ASL) is an emerging technique for the assessment of myocardial perfusion. ASL does not require any contrast agents, and therefore can be used in patients with renal failure, and can be performed continuously during an intervention. Furthermore, ASL has the potential to provide quantitative measurement of regional myocardial blood flow (MBF) in ml-...

OBJECTIVE Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. RESEARCH DESIGN AND METHODS A total of 207 consecutive diabetic patients who were unable to undergo exercise stress testing underwen...

conclusions the prevalence of undiagnosed ihd in the hd patients was considerable. we, therefore, suggest that ihd be assessed in hd patients, especially those at high risk due to positive family history of cad, hypertension, left ventricular hypertrophy, diabetes mellitus, kt/v < 1.2, low ferritin levels, and high levels of intact parathyroid hormone. results sixty-nine hd patients were studie...

introduction: we aimed to investigate of effect of left bundle branch block (lbbb) on perfusion and functional parameters in dipyridamole tc99m-mibi gated myocardial perfusion spect which may be helpful in interpretation of myocardial perfusion imaging. methods: we studied 70 patients with low pre-test probability of coronary artery disease in two groups:  35 patients with lbbb and  35 subjects...

Background Quantification of myocardial blood flow (MBF) using first-pass perfusion MRI has potential to objectively evaluate ischemic heart disease. While considerable development and clinical research has been conducted during the past two decades on this topic, there lacks a perfusion flow mapping solution that runs on the MRI scanner and produces MBF maps immediately following the perfusion...

Background Among the spectrum of patients with coronary artery disease (CAD), those suffering from high-grade stenosis are at a significantly elevated risk for adverse events [1]. Such high-grade disease may result in the so-called “coronary steal” phenomenon under vasodilator stress [2] thereby inducing wall-motion abnormalities (WMAs) in the affected territories, referred to as transient isch...

H. Pedersen, S. Ringgaard, W. Y. Kim The MR Research Centre, Skejby Hospital, Aarhus University Hospital, Aarhus N, Denmark INTRODUCTION Quantitative analysis of myocardial perfusion using free-breathing first-pass perfusion MRI is degraded by respiratory induced motion of the heart. Conventional strategies to correct this motion include the manual alignment of each image to fit a reference ima...

BACKGROUND Cadmium-zinc-telluride (CZT) solid-state detectors have been recently introduced into the field of myocardial perfusion imaging. The aim of this study was to prospectively compare the diagnostic performance of the CZT high-speed gamma camera (Discovery NM 530c) with that of the standard 3-head gamma camera in the same group of patients. METHODS AND RESULTS The study group consisted...