There is much symptomatic similarity between acute kidney disease and acute heart disease. Both may present with shortness of breath and chest discomfort, and thus it is not surprising that biomarkers of acute myocardial and renal disease often coexist in many physicians' diagnostic work-up schedules. In this review we explore the similarities and differences between current and future tests of...

Aim. To determine the prognostic significance of N-terminal pro-brain natriuretic peptide (NT-proBNP) and soluble ST2 (sST2) in patients with post-myocardial infarction heart failure after a coronavirus disease 2019 (COVID-19) Material methods. Three following groups were formed: group I (main), who underwent inpatient treatment for COVID-19, cause (HF) was prior Q-wave myocardial infarction; I...

RATIONALE Long noncoding RNAs represent a novel class of molecules regulating gene expression. Long noncoding RNAs are present in body fluids, but their potential as biomarkers was never investigated in cardiovascular disease. OBJECTIVE To study the role of long noncoding RNAs as potential biomarkers in heart disease. METHODS AND RESULTS Global transcriptomic analyses were done in plasma RN...

On the other hand, with the emergence of new markers, basically troponins and CKMB mass (“biomarkers of myocardial necrosis”), new evidence began to emerge. For example, many patients who were categorized as having unstable angina have received a diagnosis of acute myocardial infarction without ST segment elevation, because these biomarkers are more sensitive than the enzymes previously used. O...

BACKGROUND Several biomarkers have individually been shown to be useful for risk stratification in patients with acute myocardial infarction (MI). The optimal multimarker strategy remains undefined. METHODS AND RESULTS Biomarkers representing different pathobiological axes were studied, including myocardial stress/structural changes (NT-pro B-type natriuretic peptide [NT-proBNP], midregional ...