when pooled immunoglobulin g (igg) from patients with multiple sclerosis (ms) was used to probe a human fetal spinal cord λgt 11 cdna library, the igg was found to bind to a predicted epitope of human mitochondrial nd4 sequence. to investigate the involvement of the nd4 as an autoantigen in ms, we determined the presence of specific antibody in the serum of ms patients and serum samples of some...

Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and inflammatory nervous system disease. It leads to the loss of myelin in the white matter of brain, spinal cord and optic nerves. As a chronic disease with sudden and unpredictable Side effects and complications of the disease will lead to disability and dependency in life. Causes neurologic symptoms and sig. The purpose of the p...

how to cite this article: inaloo s, haghbin s. multiple sclerosis in children. iran j child neurol. 2013 spring;7(2):1-10.   multiple sclerosis (ms) is the most important immune-mediated demyelinated disease of human which is typically the disease of young adults. a total of 4% to 5% of ms population are pediatric. pediatric ms is defined as the appearance of ms before the age of sixteen. about...

Multiple Sclerosis is a chronic inflammatory disease. It characterized by demyelinating lesions throughout the central nervous system. Patients suffering from multiple sclerosis constitute vulnerable population to coronavirus disease-2019. This review focuses on effects of disease-2019 relapse and symptom exacerbation in patients their treatment. highlights how blood-brain barrier may be compro...

multiple sclerosis (ms) is an autoimmune disease of the central nervous system (cns) which causes demyelination of the nerve fibers. the etiology of this disease is not well understood but it is believed that t helpers play a central role in ms. numerous findings support the view that th17 cells play an essential role in pathogenesis of ms and il-17 secreting t (th17) cells have a role in infla...

background: multiple sclerosis (ms) is a chronic disease characterized by degradation of the central nervous system myelin which may impair the balance of patients. core stability exercises have been the focus of attention for repairing the stability of some patients.   objectives: to assess the effect of core stability exercise on the balance of patients with multiple sclerosis. materials and ...

background: multiple sclerosis (ms) is the most common demyelinating disease. an autoimmune basis has been confirmed for pathogenesis of ms. prolactin (prl) has roles in these mechanisms. its serum levels change in ms according to some reports. the purpose of this study was to survey these changes in ms patients. methods: sixty ms patients were included in this cross-sectional study. the same n...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: there is a broad variation in reported frequencies of seizure in multiple sclerosis (ms). in this study, the seizure and its characteristics analyzed among a large group of patients with ms. materials and methods: we reviewed the medical records of all definite ms patients referred to the ms clinic of kashani h...