Nuclear imaging techniques, including primarily positron emission tomography (PET) and single-photon emission computed tomography (SPECT), can provide quantitative information for a biological event in vivo with ultra-high sensitivity, however, the comparatively low spatial resolution is their major limitation in clinical application. By convergence of nuclear imaging with other imaging modalit...

Pericardial disease is an important cause of morbidity and mortality in patients with cardiovascular disease. Inflammatory diseases of the pericardium constitute a spectrum ranging from acute pericarditis to chronic constrictive pericarditis. Other important entities that involve the pericardium include benign and malignant pericardial masses, pericardial cysts, and diverticula, as well as cong...

Discoveries in the field of molecular biology over the past two decades have radically altered how bioengineers approach biological and diagnostic imaging. The genetic and biochemical mechanisms underlying cancer, for example, provide new opportunities for detection, classification, and treatment of multiform, complex disease processes. Cancer is a principal application of molecular imaging, as...